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49 条搜索结果 for FcRn
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria
Authors: Stian Foss , Siri A Sakya, Leire Aguinagalde, Marta Lustig, Jutamas Shaughnessy, Ana Rita Cruz , Lisette Scheepmaker, Line Mathiesen, Fulgencio Ruso-Julve, Aina Karen Anthi, Torleif Tollefsrud Gjølberg
Journal: Nature Communications
PubMed ID: 38453922
Doi: 10.1038/s41467-024-46321-9
Products & Services: Gene Synthesis   
Evidence for the Role of a Second Fc-Binding Receptor in Placental IgG Transfer in Nonhuman Primates
Authors: Yvonne J Rosenberg, Tracy Ordonez, Urjeet S Khanwalkar, Philip Barnette, Shilpi Pandey, Iara M Backes, Claire E Otero, Benjamin S Goldberg, Andrew R Crowley, David A Leib, Mariya B Shapiro, Xiaoming Jiang, Lori A Urban, Jonathan Lees, Ann J Hessell, Sallie Permar, Nancy L Haigwood, Margaret E Ackerman
Journal: MBio
PubMed ID: 36946726
Doi: 10.1128/mbio.00341-23
Products & Services: Recombinant Proteins   
Design of a chimeric ACE-2/Fc-silent fusion protein with ultrahigh affinity and neutralizing capacity for SARS-CoV-2 variants
Authors: Neil M Bodie, Rina Hashimoto, David Connolly, Jennifer Chu, Kazuo Takayama, Bruce D Uhal
Journal: Antib Ther
PubMed ID: 36741194
Doi: 10.1093/abt/tbad001
Products & Services: Proteins, Expression, Isolation and Analysis   
Autoimmune haemolytic anaemia
Authors: María Argüello Marina, Montserrat López Rubio, Lucía Castilla García
Journal: Med Clin (Barc)
PubMed ID: 36334945
Doi: 10.1016/j.medcli.2022.07.021
Products & Services: Polyclonal Antibody Services   
An albumin-angiotensin converting enzyme 2-based SARS-CoV-2 decoy with FcRn-driven half-life extension
Authors: Elisabeth Fuchs, Imke Rudnik-Jansen, Anders Dinesen, Denis Selnihhin, Ole Aalund Mandrup, Kader Thiam, Jørgen Kjems, Finn Skou Pedersen, Kenneth A Howard
Journal: Acta Biomater
PubMed ID: 36162760
Doi: 10.1016/j.actbio.2022.09.048
Products & Services: Plasmid DNA Preparation   
Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life
Authors: Torleif Tollefsrud Gjølberg, Rahel Frick, Simone Mester, Stian Foss, Algirdas Grevys, Lene Støkken Høydahl, Øystein Kalsnes Jørstad, Tilman Schlothauer, Inger Sandlie, Morten C Moe, Jan Terje Andersen
Journal: Commun Biol
PubMed ID: 35982144
Doi: 10.1038/s42003-022-03787-x
Products & Services: Custom Vector Construction   
Engineered human antibodies for the opsonization and killing of
Authors: Xinhai Chen, Olaf Schneewind, Dominique Missiakas
Journal: Proc Natl Acad Sci U S A
PubMed ID: 35058363
Doi: 10.1073/pnas.2114478119
Products & Services: Proteins, Expression, Isolation and Analysis   
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life
Authors: Algirdas Grevys, Rahel Frick, Simone Mester, Karine Flem-Karlsen, Jeannette Nilsen, Stian Foss, Kine Marita Knudsen Sand, Thomas Emrich, Jens Andre Alexander Fischer, Victor Greiff, Inger Sandlie, Tilman Schlothauer, Jan Terje Andersen
Journal: iScience
PubMed ID: 35118359
Doi: 10.1016/j.isci.2022.103746
Products & Services: Mutagenesis Services   
Full-length recombinant antibodies from : production, characterization, effector function (Fc) engineering, and clinical evaluation
Authors:
Journal: MAbs
PubMed ID: 36018829
Doi: 10.1080/19420862.2022.2111748
Products & Services: Gene Synthesis   
A single injection of CM1021, a long half-life hepatocyte growth factor mimetic, increases liver mass in mice
Authors:
Journal: Biochem Biophys Rep
PubMed ID: 34977363
Doi: 10.1016/j.bbrep.2021.101186
Products & Services: Plasmid DNA Preparation