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Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)

Authors: Lester J Lambert, Stefan Grotegut, Maria Celeridad, Palak Gosalia, Laurent Js De Backer, Andrey A Bobkov, Sumeet Salaniwal, Thomas Dy Chung, Fu-Yue Zeng, Ian Pass, Paul J Lombroso, Nicholas Dp Cosford, Lutz Tautz

Journal: Int J Mol Sci

PubMed ID: 33922601

Doi: 10.3390/ijms22094417

Products & Services: Mammalian Expression

targeting of lentiviral vectors pseudotyped with the Tupaia paramyxovirus H glycoprotein bearing a cell-specific ligand

Authors: Takele Argaw, Michael P Marino, Andrew Timmons, Lindsey Eldridge, Kazuyo Takeda, Pingjuan Li, Anna Kwilas, Wu Ou, Jakob Reiser

Journal: Mol Ther Methods Clin Dev

PubMed ID: 34141822

Doi: 10.1016/j.omtm.2021.04.012

Products & Services: Codon Optimization

Mapping the degradation pathway of a disease-linked aspartoacylase variant

Authors: Sarah K Gersing, Yong Wang, Martin Grønbæk-Thygesen, Caroline Kampmeyer, Lene Clausen, Martin Willemoës, Claes Andréasson, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: PLoS Genet

PubMed ID: 33914734

Doi: 10.1371/journal.pgen.1009539

Products & Services: Gene Synthesis

ZC3H4 restricts non-coding transcription in human cells

Authors: Chris Estell, Lee Davidson, Pieter C Steketee, Adam Monier, Steven West

Journal: Elife

PubMed ID: 33913806

Doi: 10.7554/eLife.67305

Products & Services: Custom Vector Construction

Grb2 binding induces phosphorylation-independent activation of Shp2

Authors: Chi-Chuan Lin, Lukasz Wieteska, Kin Man Suen, Arnout P Kalverda, Zamal Ahmed, John E Ladbury

Journal: Commun Biol

PubMed ID: 33795832

Doi: 10.1038/s42003-021-01969-7

Products & Services: Catalog Antibodies

Intrinsically disordered substrates dictate SPOP subnuclear localization and ubiquitination activity

Authors: Emery T Usher, Nafiseh Sabri, Roman Rohac, Amie K Boal, Tanja Mittag, Scott A Showalter

Journal: J Biol Chem

PubMed ID: 33894201

Doi: 10.1016/j.jbc.2021.100693

Products & Services: Plasmid DNA Preparation

Tick Importin-α Is Implicated in the Interactome and Regulome of the Cofactor Subolesin

Authors: Sara Artigas-Jerónimo, Margarita Villar, Alejandro Cabezas-Cruz, Grégory Caignard, Damien Vitour, Jennifer Richardson, Sandrine Lacour, Houssam Attoui, Lesley Bell-Sakyi, Eleonore Allain, Ard M Nijhof, Nina Militzer, Sophia Pinecki Socias, José de la Fuente

Journal: Pathogens

PubMed ID: 33920361

Doi: 10.3390/pathogens10040457

Products & Services: Bacterial Expression

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer

Authors: Radhika R Gudi, Harinarayanan Janakiraman, Philip H Howe, Viswanathan Palanisamy, Chenthamarakshan Vasu

Journal: Oncotarget

PubMed ID: 33889303

Doi: 10.18632/oncotarget.27932

Products & Services: Custom Vector Construction

Molecular basis for Ras suppressor-1 binding to PINCH-1 in focal adhesion assembly

Authors: Koichi Fukuda, Fan Lu, Jun Qin