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S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis

Authors: Dongqin Chen, Fengsheng Hao, Huiqi Mu, Nagib Ahsan, Jay J Thelen, Gary Stacey

Journal: Nat Commun

PubMed ID: 33980819

Doi: 10.1038/s41467-021-22854-1

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The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation

Authors: Priscila Sutto-Ortiz, Sergey Tcherniuk, Nina Ysebaert, Pravien Abeywickrema, Mathieu Noël, Alice Decombe, Françoise Debart, Jean-Jacques Vasseur, Bruno Canard, Dirk Roymans, Peter Rigaux, Jean-François Eléouët, Etienne Decroly

Journal: PLoS Pathog

PubMed ID: 33956914

Doi: 10.1371/journal.ppat.1009562

Products & Services: Bacterial Expression

Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus

Authors: Qingxing Wang, Qilin Xin, Weijuan Shang, Weiwei Wan, Gengfu Xiao, Lei-Ke Zhang

Journal: Viruses

PubMed ID: 34070281

Doi: 10.3390/v13060976

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Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy

Authors: Ethan W Hass, Zachary A Sorrentino, Grace M Lloyd, Nikolaus R McFarland, Stefan Prokop, Benoit I Giasson

Journal: Acta Neuropathol Commun

PubMed ID: 33941284

Doi: 10.1186/s40478-021-01173-y

Products & Services: Peptide Synthesis

Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency

Authors: Seula Shin, Hao Zhou, Chenxi He, Yanjun Wei, Yunfei Wang, Takashi Shingu, Ailiang Zeng, Shaobo Wang, Xin Zhou, Hongtao Li, Qiang Zhang, Qinling Mo, Jiafu Long, Fei Lan, Yiwen Chen, Jian Hu

Journal: Nat Commun

PubMed ID: 34021134

Doi: 10.1038/s41467-021-22782-0

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Process development and scale-up optimization of the SARS-CoV-2 receptor binding domain-based vaccine candidate, RBD219-N1C1

Authors: Jungsoon Lee, Zhuyun Liu, Wen-Hsiang Chen, Junfei Wei, Rakhi Kundu, Rakesh Adhikari, Joanne Altieri Rivera, Portia M Gillespie, Ulrich Strych, Bin Zhan, Peter J Hotez, Maria Elena Bottazzi

Journal: Appl Microbiol Biotechnol

PubMed ID: 33959781

Doi: 10.1007/s00253-021-11281-3

Products & Services: Mammalian Expression

Kinetic and structural parameters governing Fic-mediated adenylylation/AMPylation of the Hsp70 chaperone, BiP/GRP78

Authors: Anwesha Sanyal, Erica A Zbornik, Ben G Watson, Charles Christoffer, Jia Ma, Daisuke Kihara, Seema Mattoo

Journal: Cell Stress Chaperones

PubMed ID: 33942205

Doi: 10.1007/s12192-021-01208-2

Products & Services: PCR Cloning and Subcloning

Antigen-driven autoantibody production in lungs of interstitial lung disease with autoimmune disease

Authors: Masaru Takeshita, Katsuya Suzuki, Maho Nakazawa, Hirofumi Kamata, Makoto Ishii, Yoshitaka Oyamada, Hisaji Oshima, Tsutomu Takeuchi

Journal: J Autoimmun

PubMed ID: 34034155

Doi: 10.1016/j.jaut.2021.102661

Products & Services: Protein and Antibody Isolation

Correction to: Assessment of the mechanism of drug resistance in Trichophyton mentagrophytes in response to various substances

Authors: Chenwen Xiao, Jiaoyu Wang, Zhenfeng Liao, Yee Huang, Quanan Ji, Yan Liu, Fei Su, Lijun Xu, Qiang Wei, Yao Pan, Ke Li, Guolian Bao

Journal: BMC Genomics

PubMed ID: 34011270

Doi: 10.1186/s12864-021-07630-1

Products & Services: Protein Tools

Reenacting the Birth of a Function: Functional Divergence of HIUases and Transthyretins as Inferred by Evolutionary and Biophysical Studies

Authors: Lucas Carrijo de Oliveira, Mariana Amalia Figueiredo Costa, Natan Gonçalves Pedersolli, Fernanda Aparecida Heleno Batista, Ana Carolina Migliorini Figueira, Rafaela Salgado Ferreira, Ronaldo Alves Pinto Nagem, Laila Alves Nahum, Lucas Bleicher

Journal: J Mol Evol

PubMed ID: 33956179

Doi: 10.1007/s00239-021-10010-8

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