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The HER2 S310F Mutant Can Form an Active Heterodimer with the EGFR, Which Can Be Inhibited by Cetuximab but Not by Trastuzumab as well as Pertuzumab.

Authors: Shin JW,, Kim S,, Ha S,, Choi B, Kim S, Im SA,,, Yoon TY, Chung J,.

Journal: Biomolecules

PubMed ID: 31635022

Doi: 10.3390/biom9100629

Products & Services: Gene Synthesis

Reduction of Global H3K27me3 Enhances HER2/ErbB2 Targeted Therapy

Authors: Hirukawa A, Singh S, Wang J, Rennhack JP, Swiatnicki M, Sanguin-Gendreau V, Zuo D, Daldoul K, Lavoie C, Park M, Andrechek ER, Westbrook TF, Harris LN, Varadan V, Smith HW, Muller WJ

Journal: Cell Rep

PubMed ID: 31597089

Doi: 10.1016/j.celrep.2019.08.105

Products & Services: Catalog Antibodies

A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin.

Authors: CostalesMatthew G，HochDominic G，AbeggDaniel，Childs-DisneyJessica L，VelagapudiSai Pradeep，AdibekianAlexander，DisneyMatth

Journal: J. Am. Chem. Soc.

PubMed ID: 30726072

Doi: 10.1021/jacs.8b10558

Products & Services: Molecular Biology Reagents

Evaluation of recombinant adenovirus vectors and adjuvanted protein as a heterologous prime-boost strategy using HER2 as a model antigen.

Authors: Haq K, Jia Y, Elahi SM, MacLean S, Akache B, Gurnani K, Chattopadhyay A, Nazemi-Moghaddam N, Gilbert R, McCluskie MJ, Weeratna RD.

Journal: Vaccine

PubMed ID: 31506193

Doi: 10.1016/j.vaccine.2019.08.079

Products & Services: Custom Vector Construction

Sequential Anti-PD1 Therapy Following Dendritic Cell Vaccination Improves Survival in a HER2 Mammary Carcinoma Model and Identifies a Critical Role for CD4 T Cells in Mediating the Response

Authors: Kodumudi KN, Ramamoorthi G, Snyder C, Basu A, Jia Y, Awshah S, Beyer AP, Wiener D, Lam L, Zhang H, Greene MI, Costa RLB, Czerniecki BJ, .

Journal: Front Immunol

PubMed ID: 31475002

Doi: 10.3389/fimmu.2019.01939

Products & Services: Protein Electrophoresis and Western

GM-CSF Promotes Antitumor Immunity by Inducing Th9 Cell Responses.

Authors: Kim IK,, Koh CH, Jeon I, Shin KS, Kang TS, Bae EA, Seo H, Ko HJ,, Kim BS, Chung Y, Kang CY,.

Journal: Cancer Immunol Res

PubMed ID: 30728152

Doi: 10.1158/2326-6066.CIR-18-0518

Products & Services: ORF cDNA Clones/MolecularCloud

MET activation confers resistance to cetuximab， and prevents HER2 and HER3 upregulation in head and neck cancer.

Authors: NovoplanskyOfra，FuryMatthew，PrasadManu，YegodayevKsenia，ZoreaJonathan，CohenLimor，PelossofRaphael，CohenLiz，KatabiNora，CecchiFabiola，JoshuaBen-Zion，PopovtzerAron，BaselgaJose，ScaltritiMaurizio，ElkabetsM

Journal: Int. J. Cancer

PubMed ID: 30694565

Doi: 10.1002/ijc.32170

Products & Services: Catalog Peptides

Expression and function of voltage gated proton channels (HV 1) in MDA-MB-231 cells

Authors: Dan J. Bare, Vladimir V. Cherny, View Thomas E. DeCoursey, Abde M. Abukhdeir, Deri Morgan

Journal: biorxiv

Doi: 10.1101/2019.12.23.886945

Products & Services: Gene Synthesis

Trop2 is a potential biomarker for the promotion of EMT in human breast cancer.

Authors: ZhaoWei，KuaiXingwang，ZhouXueyi，JiaLizhou，WangJinsong，YangXiaobing，TianZhidan，WangXiaolei，LvQian，WangBin，ZhaoYoucai，HuangWe

Journal: Oncol. Rep.

PubMed ID: 29901160

Doi: 10.3892/or.2018.6496

Products & Services: DNA Sequencing

A HER2 bispecific antibody can be efficiently expressed in with potent cytotoxicity.

Authors: LinLimin，LiLi，ZhouChanghua，LiJing，LiuJiayu，ShuRui，DongBin，LiQing，WangZ

Journal: Oncol Lett

PubMed ID: 29963199

Doi: 10.3892/ol.2018.8698

Products & Services: Catalog Antibody

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