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Self-inhibitory peptides targeting the MtrCDE efflux pump increase antibiotic susceptibility

Authors: Benjamin J Evert, Valentin A Slesarenko, Jilsy M J Punnasseril, Jian Zhan, Yaoqi Zhou, Evgeny A Semchenko, Kate L Seib

Journal: Antimicrob Agents Chemother

PubMed ID: 34633841

Doi: 10.1128/AAC.01542-21

Products & Services: Peptide Synthesis

Knockdown of circ_0011946 targets miR-216a-5p/BCL2L2 axis to regulate proliferation, migration, invasion and apoptosis of oral squamous cell carcinoma cells

Authors: Ying Zhou, Shuhong Zhang, Zhonghan Min, Zhongwei Yu, Huaiwei Zhang, Jiao Jiao

Journal: BMC Cancer

PubMed ID: 34620126

Doi: 10.1186/s12885-021-08779-4

Products & Services: Custom DNA/RNA Oligos

Biochemical and structural studies of two tetrameric nucleoside 2'-deoxyribosyltransferases from psychrophilic and mesophilic bacteria: Insights into cold-adaptation

Authors: Jesús Fernández-Lucas, Iván Acebrón, Ruiying Y Wu, Yohana Alfaro, Javier Acosta, Pierre A Kaminski, Miguel Arroyo, Andrzej Joachimiak, Boguslaw P Nocek, Isabel De la Mata, José M Mancheño

Journal: Int J Biol Macromol

PubMed ID: 34624379

Doi: 10.1016/j.ijbiomac.2021.09.164

Products & Services: Molecular Biology Reagents

Domain-specific biochemical and serological characterization of SARS-CoV-2 nucleocapsid protein

Authors: Chao Wu, Abraham J Qavi, Austin B Moyle, Nicole D Wagner, Asmaa Hachim, Niloufar Kavian, Aidan R Cole, Joyce Sweeney-Gibbons, Henry W Rohrs, J S Malik Peiris, Christopher F Basler, Michael L Gross, Sophie A Valkenburg, Christopher W Farnsworth, Gaya K Amarasinghe, Daisy W Leung

Journal: STAR Protoc

PubMed ID: 34642671

Doi: 10.1016/j.xpro.2021.100906

Products & Services: Gene Synthesis

Protective effect of sargahydroquinoic acid against Aβ-evoked damage via PI3K/Akt mediated Nrf2 antioxidant defense system

Authors: Jeong-Hyun Yoon, Kumju Youn, Mira Jun

Journal: Biomed Pharmacother

PubMed ID: 34619494

Doi: 10.1016/j.biopha.2021.112271

Products & Services: Protein and Antibody Isolation

Topmouth culter melanocortin-3 receptor: regulation by two isoforms of melanocortin-2 receptor accessory protein 2

Authors: Ren-Lei Ji, Lu Huang, Yin Wang, Ting Liu, Si-Yu Fan, Min Tao, Ya-Xiong Tao

Journal: Endocr Connect

PubMed ID: 34678761

Doi: 10.1530/EC-21-0459

Products & Services: Nucleic Acid Purification

Determining folding and binding properties of the C-terminal SH2 domain of SHP2

Authors: Caterina Nardella, Francesca Malagrinò, Livia Pagano, Serena Rinaldo, Stefano Gianni, Angelo Toto

Journal: Protein Sci

PubMed ID: 34605082

Doi: 10.1002/pro.4201

Products & Services: Mutagenesis Services

Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients

Authors: Jonathan Marable, Damien Ruiz, Anil K Jaiswal, Ritankar Bhattacharya, Robert Pantazes, Payal Agarwal, Amol S Suryawanshi, Deepa Bedi, Amarjit Mishra, Bruce F Smith, Maninder Sandey

Journal: Sci Rep

PubMed ID: 34675296

Doi: 10.1038/s41598-021-00325-3

Products & Services: Endotoxin Detection & Removal System

The Small Metal-Binding Protein SmbP Simplifies the Recombinant Expression and Purification of the Antimicrobial Peptide LL-37

Authors: David A Perez-Perez, Teresa de J Villanueva-Ramirez, Adriana E Hernandez-Pedraza, Nestor G Casillas-Vega, Patricia Gonzalez-Barranco, Xristo Zarate

Journal: Antibiotics (Basel)

PubMed ID: 34680851

Doi: 10.3390/antibiotics10101271

Products & Services: DNA Sequencing Gene Synthesis

Circular RNA circ_0090231 promotes atherosclerosis in vitro by enhancing NLR family pyrin domain containing 3-mediated pyroptosis of endothelial cells

Authors: Yishan Ge, Wenwu Liu, Wei Yin, Xuebin Wang, Jie Wang, Xiaoqing Zhu, Shengkai Xu

Journal: Bioengineered

PubMed ID: 34637670

Doi: 10.1080/21655979.2021.1989260

Products & Services: DNA Sequencing

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