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CHAMP1 complex directs heterochromatin assembly and promotes homology-directed DNA repair

Authors: Feng Li, Tianpeng Zhang, Aleem Syed, Amira Elbakry, Noella Holmer, Huy Nguyen, Sirisha Mukkavalli, Roger A Greenberg, Alan D D'Andrea

Journal: Nature Communications

PubMed ID: 39962076

Doi: 10.1038/s41467-025-56834-6

Products & Services: CRISPR Plasmids

Structural basis of ssDNA-guided NADase activation of prokaryotic SPARTA system

Authors: Rong Hu, Chenmin Guo, Xiaotian Liu, Yuanyi Lin, Zixin Yang, Zhixin Li, Ye Yang, Erman Ma, Yiyi Li, Jiyun Chen, Liang Liu

Journal: Nucleic Acids Res

PubMed ID: 39997222

Doi: 10.1093/nar/gkaf110

Products & Services: Gene Synthesis

Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling

Authors: Jeonghyeon Kwon, Haruya Kawase, Kenny Mattonet, Stefan Guenther, Lisa Hahnefeld, Jamal Shamsara, Jan Heering, Michael Kurz, Sina Kirchhofer, Cornelius Krasel, Michaela Ulrich, Margherita Persechino, Sripriya Murthy, Cesare Orlandi, Christian D Sadik, Gerd Geisslinger, Moritz Bünemann, Peter Kolb, Stefan Offermanns, Nina Wettschureck

Journal: Nature Communications

PubMed ID: 39920161

Doi: 10.1038/s41467-025-56713-0

Products & Services: Peptide Synthesis

Nucleotide-induced hyper-oligomerization inactivates transcription termination factor ρ

Authors: Bing Wang, Nelly Said, Tarek Hilal, Mark Finazzo, Markus C Wahl, Irina Artsimovitch

Journal: Nature Communications

PubMed ID: 39952913

Doi: 10.1038/s41467-025-56824-8

Products & Services: Protein Electrophoresis and Western

Distinct immunogenicity outcomes of DNA vaccines encoding malaria transmission-blocking vaccine target antigens Pfs230D1M and Pvs230D1

Authors: Yi Cao , Maisa da Silva Araujo , Cynthia G Lorang , Najara Akira Costa Dos Santos , Abhai Tripathi , Joseph Vinetz , Nirbhay Kumar

Journal: Vaccine

PubMed ID: 39787798

Doi: 10.1016/j.vaccine.2024.126696

Products & Services: Gene Synthesis Plasmid DNA Preparation

Establishment of an indirect ELISA method for detecting bovine coronavirus antibodies based on N protein

Authors: Qiang Liu , Xiaoxia Niu , Lingling Jiang , Gang Zhang , Pu Wang , Sinong Zhang , Weifeng Gao , Huichen Guo, Yujiong Wang and Yong Li

Journal: Frontiers in Veterinary Science

Doi: 10.3389/fvets.2025.1530870

Products & Services: Plasmid DNA Preparation

In vitro reconstitution of meiotic DNA double-strand-break formation

Authors: Xinzhe Tang , Zetao Hu , Jian Ding , Meixia Wu , Pin Guan , Yawei Song , Yue Yin , Wei Wu , Jinbiao Ma , Ying Huang , Ming-Han Tong

Journal: Nature

PubMed ID: 39972125

Doi: doi.org/10.1038/s41586-024-08551-1

Products & Services: Custom DNA/RNA Oligos

Identifying Exifone as a Dual-Target Agent Targeting Both SARS-CoV-2 3CL Protease and the ACE2/S-RBD Interaction Among Clinical Polyphenolic Compounds

Authors: Jiani Lu、Yan Tang、Hongtao Li、Xixiang Chen、Pengcheng Qin、Jianrong Xu、Weihua Li 和 Lili Chen

Journal: International Journal of Molecular Sciences

Doi: doi.org/10.3390/ijms26052243

Products & Services: Plasmid DNA Preparation

Polyamine-Depleting Hydrogen-Bond Organic Frameworks Unleash Dendritic Cell and T Cell Vigor for Targeted CRISPR/Cas-Assisted Cancer Immunotherapy

Authors: Yongchun Pan, Fei Zeng, Xiaowei Luan, Guanzhong He, Shurong Qin, Qianglan Lu, Bangshun He, Xin Han, Yujun Song

Journal: Adv Mater

PubMed ID: 39972681

Doi: 10.1002/adma.202411886

Products & Services: Recombinant Proteins

A truncated pre-F protein mRNA vaccine elicits an enhanced immune response and protection against respiratory syncytial virus

Authors: Min Lin, Yifan Yin, Xiaomeng Zhao, Chen Wang, Xueqing Zhu, Letao Zhan, Li Chen, Siling Wang, Xue Lin, Jun Zhang, Ningshao Xia, Zizheng Zheng

Journal: Nat Commun

PubMed ID: 39910047

Doi: 10.1038/s41467-025-56302-1

Products & Services: Protein and Antibody Isolation

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