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Pathway-instructed therapeutic selection of ruxolitinib reduces neuroinflammation in fungal postinfectious inflammatory syndrome

Authors: Jessica C Hargarten, Kenneth Ssebambulidde, Seher H Anjum, Malcolm J Vaughan, Jintao Xu, Anutosh Ganguly, Brittany Dulek, Francisco Otaizo-Carrasquero, Brian Song, Sijia Tao, Yoon-Dong Park, Terri L Scott, Tracey-Ann Höltermann, Raymond F Schinazi, Prashant Chittiboina, Bridgette Jeanne Billioux, Dima A Hammoud, Michal A Olszewski, Peter R Williamson

Journal: SCIENCE ADVANCES

PubMed ID: 40117367

Doi: 10.1126/sciadv.adi9885

Products & Services: Protein Electrophoresis and Western

Reprogramming yeast metabolism for customized starch-rich micro-grain through low-carbon microbial manufacturing

Authors: Zhihui Shi, Zhaoyu Xu, Weihe Rong, Hongbing Sun, Hongyi Zhou, Qianqian Yuan, Aixuan Xiao, Hongfei Ma, Tao Cai, Guokun Wang, Yanhe Ma

Journal: Nature Communications

PubMed ID: 40118900

Doi: 10.1038/s41467-025-58067-z

Products & Services: Custom Vector Construction

Acute diacylglycerol production activates critical membrane-shaping proteins leading to mitochondrial tubulation and fission

Authors: Joshua G Pemberton, Krishnendu Roy, Yeun Ju Kim, Tara D Fischer, Vijay Joshi, Elizabeth Ferrer, Richard J Youle, Thomas J Pucadyil, Tamas Balla

Journal: Nature Communications

PubMed ID: 40102394

Doi: 10.1038/s41467-025-57439-9

Products & Services: Custom Vector Construction

The structural basis for the human procollagen lysine hydroxylation and dual-glycosylation

Authors: Junjiang Peng, Wenguo Li, Deqiang Yao, Ying Xia, Qian Wang, Yan Cai, Shaobai Li, Mi Cao, Yafeng Shen, Peixiang Ma, Rijing Liao, Jie Zhao, An Qin, Yu Cao

Journal: Nature Communications

PubMed ID: 40069201

Doi: 10.1038/s41467-025-57768-9

Products & Services: Protein and Antibody Isolation

FGF2 Mediated USP42-PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

Authors: Nanfei Yang, Qiang Tian, Zhenli Lei, Shuxin Wang, Nan Cheng, Zhen Wang, Xianqin Jiang, Xuqun Zheng, Wenjing Xu, Minyan Ye, Longwei Zhao, Meiyun Wen, Jianlou Niu, Weijian Sun, Pingping Shen, Zhifeng Huang, Xiaokun Li

Journal: Advanced Science

PubMed ID: 40091484

Doi: 10.1002/advs.202408724

Products & Services: Recombinant Proteins

Transport and InsP8 gating mechanisms of the human inorganic phosphate exporter XPR1

Authors: Qinyu Zhu, Madeleine F Yaggi, Nikolaus Jork, Henning J Jessen, Melinda M Diver

Journal: Nature Communications

PubMed ID: 40113814

Doi: 10.1038/s41467-025-58076-y

Products & Services: Protein and Antibody Isolation

Orally delivered toxin–binding protein protects against diarrhoea in a murine cholera model

Authors: Marcus Petersson, Franz G Zingl, Everardo Rodriguez-Rodriguez, Jakob K H Rendsvig, Heidi Heinsøe, Emma Wenzel Arendrup, Natalia Mojica, Dario Segura Peña, Nikolina Sekulić, Ute Krengel, Monica L Fernández-Quintero, Timothy P Jenkins, Lone Gram, Matthew K Waldor, Andreas H Laustsen, Sandra Wingaard Thrane

Journal: Nature Communications

PubMed ID: 40108169

Doi: 10.1038/s41467-025-57945-w

Products & Services: Neoantigen Peptide Service

Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining

Authors: Yan Wang, Fuyuan Shen, Chen Zhao, Jiali Li, Wen Wang, Yamu Li, Jia Gan, Haojian Zhang, Xuefeng Chen, Qiang Chen, Fangyu Wang, Ying Liu, Yan Zhou

Journal: Nucleic Acids Res

PubMed ID: 40114375

Doi: 10.1093/nar/gkaf200

Products & Services: Peptide Synthesis

Integrative in silico and biochemical analyses demonstrate direct Arl3-mediated ODA16 release from the intraflagellar transport machinery

Authors: Jiaolong Wang, Rune T Kidmose, Niels Boegholm, Nevin K Zacharia, Mads B Thomsen, Anni Christensen, Tara Malik, Karl Lechtreck, Esben Lorentzen

Journal: The Journal of biological chemistry

PubMed ID: 39880089

Doi: 10.1016/j.jbc.2025.108237

Products & Services: Gene Synthesis Codon Optimization

Splenic red pulp macrophages eliminate the liver-resistant Streptococcus pneumoniae from the blood circulation of mice

Authors: Haoran An, Yijia Huang, Zhifeng Zhao, Kunpeng Li, Jingjing Meng, Xueting Huang, Xianbin Tian, Hongyu Zhou, Jiamin Wu, Qionghai Dai, Jing-Ren Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 40073120

Doi: 10.1126/sciadv.adq6399

Products & Services: Protein and Antibody Isolation

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