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Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer's disease

Authors: Yue Dong, Hanqiao Yu, Xueqi Li, Kelong Bian, Yayuan Zheng, Mingrui Dai, Xuejian Feng, Yao Sun, Yu He, Bin Yu, Haihong Zhang, Jiaxin Wu, Xianghui Yu, Hui Wu, Wei Kong

Journal: J Neuroinflammation

PubMed ID: 35971179

Doi: 10.1186/s12974-022-02567-y

Products & Services: Gene Synthesis

Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms

Authors: Laura J Stevens, Andrea J Pruijssers, Hery W Lee, Calvin J Gordon, Egor P Tchesnokov, Jennifer Gribble, Amelia S George, Tia M Hughes, Xiaotao Lu, Jiani Li, Jason K Perry, Danielle P Porter, Tomas Cihlar, Timothy P Sheahan, Ralph S Baric, Matthias Götte, Mark R Denison

Journal: Sci Transl Med

PubMed ID: 35482820

Doi: 10.1126/scitranslmed.abo0718

Products & Services: Plasmid DNA Preparation

assessment of simultaneous G1 cyclins silencing by a tumor-specific bidirectional promoter on the mammary tumor in nude mice

Authors: Gholamreza Mesbah, Fatemeh Namazi, Fatemeh T Shamsabadi, Zahra Maleki, Mehrab Nasirikenari, Majid Shahbazi

Journal: Front Vet Sci

PubMed ID: 36072388

Doi: 10.3389/fvets.2022.914311

Products & Services: Custom Vector Construction

Signal Peptide-rheostat Dynamics Delay Secretory Preprotein Folding

Authors: Dries Smets, Jochem Smit, Ying Xu, Spyridoula Karamanou, Anastassios Economou

Journal: J Mol Biol

PubMed ID: 35970402

Doi: 10.1016/j.jmb.2022.167790

Products & Services: Custom Vector Construction

Quorum Sensing Regulation of a Major Facilitator Superfamily Transporter Affects Multiple Streptococcal Virulence Factors

Authors: Jennifer C Chang, Reid V Wilkening, Kate M Rahbari, Michael J Federle

Journal: J Bacteriol

PubMed ID: 35938850

Doi: 10.1128/jb.00176-22

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A computational approach to rapidly design peptides that detect SARS-CoV-2 surface protein S

Authors: Maryam Hajikarimlou, Mohsen Hooshyar, Mohamed Taha Moutaoufik, Khaled A Aly, Taha Azad, Sarah Takallou, Sasi Jagadeesan, Sadhna Phanse, Kamaledin B Said, Bahram Samanfar, John C Bell, Frank Dehne, Mohan Babu, Ashkan Golshani

Journal: NAR Genom Bioinform

PubMed ID: 36004308

Doi: 10.1093/nargab/lqac058

Products & Services: Catalog Antibodies

Growth State-Dependent Expression of Arachidonate Lipoxygenases in the Human Endothelial Cell Line EAhy926

Authors: Mohammad G Sabbir, Jeffrey T Wigle, Carla G Taylor, Peter Zahradka

Journal: Cells

PubMed ID: 36010555

Doi: 10.3390/cells11162478

Products & Services: ORF cDNA Clones/MolecularCloud

Ultrabright nanoparticle-labeled lateral flow immunoassay for detection of anti-SARS-CoV-2 neutralizing antibodies in human serum

Authors: Lun Bian , Zhaoyue Li , An He , Biru Wu , Hui Yang , Yingsong Wu , Fang Hu , Guanfeng Lin , Deqing Zhang

Journal: Biomaterials

PubMed ID: 35977850

Doi: 10.1016/j.biomaterials.2022.121694

Products & Services: Recombinant Proteins

Hormone- and antibody-mediated activation of the thyrotropin receptor

Authors: Jia Duan , Peiyu Xu , Xiaodong Luan , Yujie Ji , Xinheng He , Ning Song , Qingning Yuan , Ye Jin , Xi Cheng , Hualiang Jiang , Jie Zheng , Shuyang Zhang , Yi Jiang , H Eric Xu

Journal: Nature

PubMed ID: 35940204

Doi: 10.1038/s41586-022-05173-3

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Circular RNA hsa_circ_0007367 promotes the progression of pancreatic ductal adenocarcinoma by sponging miR-6820-3p and upregulating YAP1 expression

Authors: Haocheng Zhang, Xiaolei Ma, Luning Wang, Xinyu Li, Di Feng, Meiming Liu, Jiayang Li, Mengxing Cheng, Na Song, Xinxia Yang, Lina Ba, Yating Lei, Ruipu Zhang, Yunxiao Zhu, Wenxiao Xu, Guofen Qiao

Journal: Cell Death Dis

PubMed ID: 36008392

Doi: 10.1038/s41419-022-05188-8

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