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Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation

Authors: Pedro Madrigal, Siwei Deng, Yuliang Feng, Stefania Militi, Kim Jee Goh, Reshma Nibhani, Rodrigo Grandy, Anna Osnato, Daniel Ortmann, Stephanie Brown, Siim Pauklin

Journal: Nat Commun

PubMed ID: 36697417

Doi: 10.1038/s41467-023-36116-9

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Activity-balanced GLP-1/GDF15 dual agonist reduces body weight and metabolic disorder in mice and non-human primates

Authors: Yuanyuan Zhang, Xinyu Zhao, Xiaona Dong, Yuying Zhang, Haixia Zou, Yaoguang Jin, Wei Guo, Peng Zhai, Xu Chen, Alexei Kharitonenkov

Journal: Cell Metab

PubMed ID: 36706758

Doi: 10.1016/j.cmet.2023.01.001

Products & Services: Protein and Antibody Isolation

Spike-mediated viral membrane fusion is inhibited by a specific anti-IFITM2 monoclonal antibody

Authors: Anna Basile , Carla Zannella , Margot De Marco , Giuseppina Sanna , Gianluigi Franci , Massimiliano Galdiero , Aldo Manzin , Vincenzo De Laurenzi , Massimiliano Chetta , Alessandra Rosati , Maria Caterina Turco , Liberato Marzullo

Journal: Antiviral Res

PubMed ID: 36669656

Doi: 10.1016/j.antiviral.2023.105546

Products & Services: Monoclonal Antibody Services

α-Synuclein as a Target for Metallo-Anti-Neurodegenerative Agents

Authors: Kaiming Cao , Yang Zhu , Zhuanghao Hou , Manman Liu , Yanyan Yang , Hongze Hu , Yi Dai , Yu Wang , Siming Yuan , Guangming Huang , Jiaming Mei , Peter J Sadler , Yangzhong Liu

Journal: Angew Chem Int Ed Engl .

PubMed ID: 36345707

Doi: 10.1002/anie.202215360

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Cytochalasin B-Induced Membrane Vesicles from TRAIL-Overexpressing Mesenchymal Stem Cells Induce Extrinsic Pathway of Apoptosis in Breast Cancer Mouse Model

Authors: Daria S Chulpanova , Tamara V Pukhalskaia , Zarema E Gilazieva , Yuliya V Filina 1, Milana N Mansurova 1, Albert A Rizvanov 1, Valeriya V Solovyeva

Journal: Curr Issues Mol Biol .

PubMed ID: 36661524

Doi: 10.3390/cimb45010038

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Unusual crystal structures of MHC class I complexes reveal the elusive intermediate conformations explored during peptide editing in antigen presentation

Authors: Lenong Li, Xubiao Peng, Mansoor Batliwala, Marlene Bouvier

Journal: Res Sq

PubMed ID: 36747752

Doi: 10.21203/rs.3.rs-2500847/v1

Products & Services: Protein and Antibody Isolation

Genomewide Association Study Identifies Copy Number Variants Associated With Warfarin Dose Response and Risk of Venous Thromboembolism in African Americans

Authors: Honghong Zhang, Cristina Alarcon, Larisa H Cavallari, Edith Nutescu, Gemma L Carvill, Minoli A Perera, Wenndy Hernandez

Journal: Clin Pharmacol Ther

PubMed ID: 36507737

Doi: 10.1002/cpt.2820

Products & Services: Molecular Biology Reagents

Comprehensive Comparison of Seven SARS-CoV-2-Specific Surrogate Virus Neutralization and Anti-Spike IgG Antibody Assays Using a Live-Virus Neutralization Assay as a Reference

Authors: Marianne Graninger, Claudia Maria Jani, Elisabeth Reuberger, Katja Prüger, Philipp Gaspar, David Niklas Springer, Christian Borsodi, Lisa Weidner, Susanne Rabady, Elisabeth Puchhammer-Stöckl, Christof Jungbauer, Eva Höltl, Judith Helene Aberle, Karin Stiasny, Lukas Weseslindtner

Journal: Microbiol Spectr

PubMed ID: 36622205

Doi: 10.1128/spectrum.02314-22

Products & Services: Protein and Antibody Isolation

A linear DNA encoding the SARS-CoV-2 receptor binding domain elicits potent immune response and neutralizing antibodies in domestic cats

Authors: Antonella Conforti, Elisa Sanchez, Erika Salvatori, Lucia Lione, Mirco Compagnone, Eleonora Pinto, Fabio Palombo, Emanuela D'Acunto, Alessia Muzi, Giuseppe Roscilli, Yuhua Sun, Brian Viscount, James Hayward, Clay Shorrock, Diego G Diel, Joseph A Impellizeri, Luigi Aurisicchio

Journal: Mol Ther Methods Clin Dev

PubMed ID: 36618106

Doi: 10.1016/j.omtm.2022.12.015

Products & Services: Molecular Biology Reagents

AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer

Authors: Yongming Fu, Tuoyu Cao, Xiaorui Zou, Yubing Ye, Youhong Liu, Yuchong Peng, Tanggang Deng, Linglong Yin, Xiong Li

Journal: Oncogenesis

PubMed ID: 36593255

Doi: 10.1038/s41389-022-00446-y

Products & Services: Molecular Biology Reagents

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