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Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury

Authors: Ari Kwon, Na Young Lee, Jae-Hyun Yu, Myeung Gi Choi, Jeongwoo Park, Ja Hyun Koo

Journal: Cell Death Dis

PubMed ID: 38225223

Doi: 10.1038/s41419-024-06448-5

Products & Services: Proteins, Expression, Isolation and Analysis

Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2

Authors: Klara Lenart, Rodrigo Arcoverde Cerveira, Fredrika Hellgren, Sebastian Ols, Daniel J Sheward, Changil Kim, Alberto Cagigi, Matthew Gagne, Brandon Davis, Daritza Germosen, Vicky Roy, Galit Alter, Hélène Letscher, Jérôme Van Wassenhove, Wesley Gros, Anne-Sophie Gallouët, Roger Le Grand, Harry Kleanthous, Mimi Guebre-Xabier, Ben Murrell, Nita Patel, Gregory Glenn, Gale Smith, Karin Loré

Journal: npj Vaccines

PubMed ID: 38245545

Doi: 10.1038/s41541-024-00806-2

Products & Services: Recombinant Proteins

Orthopoxvirus-Specific T-Cell Responses in Convalescent Mpox Patients

Authors: Caroline C Traut, Joyce L Jones, Renata A Sanders, Laura R Clark, Matthew M Hamill, Georgia Stavrakis, Joel Sop, Tyler P Beckey, Sara C Keller, Elizabeth A Gilliams, Willa V Cochran, Oliver Laeyendecker, Yukari C Manabe, Heba H Mostafa, David L Thomas, Bhakti Hansoti, Kelly A Gebo, Joel N Blankson

Journal: J Infect Dis

PubMed ID: 37380166

Doi: 10.1093/infdis/jiad245

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USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication

Authors: Hannah L Mackay, Helen R Stone, Katherine Ellis, George E Ronson, Alexandra K Walker, Katarzyna Starowicz, Alexander J Garvin, Patrick van Eijk, Alina Vaitsiankova, Sobana Vijayendran, James F Beesley, Eva Petermann, Eric J Brown, Ruth M Densham, Simon H Reed, Felix Dobbs, Marco Saponaro, Joanna R Morris

Journal: biorxiv

PubMed ID: 38260523

Doi: 10.1101/2024.01.10.574674

Products & Services: Molecular Biology Reagents

PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation

Authors: Christopher Chin Sang, Gaelen Moore, Maria Tereshchenko, Michael L Nosella, Hongshan Zhang, T Reid Alderson, Morgan Dasovich, Anthony Leung, Ilya J Finkelstein, Julie D Forman-Kay, Hyun O Lee

Journal: biorxiv

PubMed ID: 38328070

Doi: 10.1101/2024.01.20.575817

Products & Services: Gene Synthesis

Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria

Authors: Sabine Poerschke, Silke Oeljeklaus, Luis Daniel Cruz-Zaragoza, Alexander Schenzielorz, Drishan Dahal, Hauke Sven Hillen, Hirak Das, Laura Sophie Kremer, Anusha Valpadashi, Mirjam Breuer, Johannes Sattmann, Ricarda Richter-Dennerlein, Bettina Warscheid, Sven Dennerlein, Peter Rehling

Journal: Cell

PubMed ID: 38199007

Doi: 10.1016/j.molcel.2023.12.013

Products & Services: Gene Synthesis

Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function

Authors: Leonardo A Parra-Rivas , Kayalvizhi Madhivanan , Brent D Aulston , Lina Wang , Dube Dheeraj Prakashchand , Nicholas P Boyer , Veronica M Saia-Cereda , Kristen Branes-Guerrero , Donald P Pizzo , Pritha Bagchi , V S Sundar , Yong Tang , Utpal Das , David A Scott , Padmini Rangamani , Yuki Ogawa , Subhojit Roy

Journal: Neuron .

PubMed ID: 38128479

Doi: 10.1016/j.neuron.2023.11.020

Products & Services: Gene Services

Choosing the right mouse model: comparison of humanized NSG and NBSGW mice for in vivo HSC gene therapy

Authors: Seunga Choo, Carl B Wolf, Heather M Mack, Mitchell J Egan, Hans-Peter Kiem, Stefan Radtke

Journal: Blood Adv

PubMed ID: 38113461

Doi: 10.1182/bloodadvances.2023011371

Products & Services: Molecular Biology Reagents

A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity

Authors: Solange Moréra, Armelle Vigouroux, Magali Aumont-Nicaise, Mohammed Ahmar, Thibault Meyer, Abbas El Sahili, Grégory Deicsics, Almudena González-Mula, Sizhe Li, Jeanne Doré, Serena Siragu, Pierre Legrand, Camille Penot, François Andrè, Denis Faure, Laurent Soulère, Yves Queneau, Ludovic Vial

Journal: Biochem J

PubMed ID: 38058289

Doi: 10.1042/BCJ20230273

Products & Services: Molecular Biology Reagents

Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study

Authors: Yunlin Zhang, Ruchi P Patel, Ki Hyun Kim, Hyungwoo Cho, Jae-Cheol Jo, Seong Hyun Jeong, Sung Yong Oh, Yoon Seok Choi, Sung Hyun Kim, Ji Hyun Lee, Mathew Angelos, Puneeth Guruprasad, Ivan Cohen, Ositadimma Ugwuanyi, Yong Gu Lee, Raymone Pajarillo, Jong Hyun Cho, Alberto Carturan, Luca Paruzzo, Guido Ghilardi, Michael Wang, Soohwan Kim, Sung-Min Kim, Hyun-Jong Lee, Ji-Ho Park, Leiguang Cui, Tae Bum Lee, In-Sik Hwang, Young-Ha Lee, Yong-Jun Lee, Patrizia Porazzi, Dongfang Liu, Yoon Lee, Jong-Hoon Kim, Jong-Seo Lee, Dok Hyun Yoon, Junho Chung, Marco Ruella

Journal: Mol Cancer

PubMed ID: 38066564

Doi: 10.1186/s12943-023-01886-9

Products & Services: Recombinant Proteins

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