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Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells

Authors: Scott Bell, Vincent McCarty, Huashan Peng, Malvin Jefri, Nuwan Hettige, Lilit Antonyan, Liam Crapper, Liam A O'Leary, Xin Zhang, Ying Zhang, Hanrong Wu, Diane Sutcliffe, Ilaria Kolobova, Thad A Rosenberger, Luc Moquin, Alain Gratton, Jelena Popic, Ilse Gantois, Patrick S Stumpf, Andreas A Schuppert, Naguib Mechawar, Nahum Sonenberg, Michel L Tremblay, Hyder A Jinnah, Carl Ernst

Journal: Stem Cell Reports

PubMed ID: 34214487

Doi: 10.1016/j.stemcr.2021.06.003

Products & Services: Recombinant Proteins

Exploring Codon Adjustment Strategies towards -Based Production of Viral Proteins Encoded by HTH1, a Novel Prophage of the Marine Bacterium

Authors: Hasan Arsın, Andrius Jasilionis, Håkon Dahle, Ruth-Anne Sandaa, Runar Stokke, Eva Nordberg Karlsson, Ida Helene Steen

Journal: Viruses

PubMed ID: 34201869

Doi: 10.3390/v13071215

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain

Authors: Chao Wu, Abraham J Qavi, Asmaa Hachim, Niloufar Kavian, Aidan R Cole, Austin B Moyle, Nicole D Wagner, Joyce Sweeney-Gibbons, Henry W Rohrs, Michael L Gross, J S Malik Peiris, Christopher F Basler, Christopher W Farnsworth, Sophie A Valkenburg, Gaya K Amarasinghe, Daisy W Leung

Journal: iScience

PubMed ID: 34095780

Doi: 10.1016/j.isci.2021.102681

Products & Services: Gene Synthesis

P300-mediated NEDD4 acetylation drives ebolavirus VP40 egress by enhancing NEDD4 ligase activity

Authors: Linliang Zhang, Shixiong Zhou, Majuan Chen, Jie Yan, Yi Yang, Linjuan Wu, Dongning Jin, Lei Yin, Mingzhou Chen, Yali Qin

Journal: PLoS Pathog

PubMed ID: 34111220

Doi: 10.1371/journal.ppat.1009616

Products & Services: Proteins, Expression, Isolation and Analysis

Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression

Authors: Meijia Qian, Fangjie Yan, Weihua Wang, Jiamin Du, Tao Yuan, Ruilin Wu, Chenxi Zhao, Jiao Wang, Jiabin Lu, Bo Zhang, Nengming Lin, Xin Dong, Xiaoyang Dai, Xiaowu Dong, Bo Yang, Hong Zhu, Qiaojun He

Journal: Acta Pharm Sin B

PubMed ID: 35024322

Doi: 10.1016/j.apsb.2021.04.003

Products & Services: Proteins, Expression, Isolation and Analysis

Arginine methylation of METTL14 promotes RNA N-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells

Authors: Xiaona Liu, Hailong Wang, Xueya Zhao, Qizhi Luo, Qingwen Wang, Kaifen Tan, Zihan Wang, Jia Jiang, Jinru Cui, Enhui Du, Linjian Xia, Wenyi Du, Dahua Chen, Laixin Xia, Shan Xiao

Journal: Nat Commun

PubMed ID: 34145242

Doi: 10.1038/s41467-021-24035-6

Products & Services: Proteins, Expression, Isolation and Analysis

Exosomes from bovine endometrial epithelial cells ensure trophoblast cell development by miR-218 targeting secreted frizzled related protein 2

Authors: Wang X,Li Q,Xie T,Yuan M,Sheng X,Qi X,Xing K,Liu F,Guo Y,Xiao L,Ni H

Journal: Journal of cellular physiology

PubMed ID: 33230823

Doi: 10.1002/jcp.30180

Products & Services: Recombinant Proteins

Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein

Authors: C Joaquín Cáceres, Stivalis Cardenas-Garcia, Aarti Jain, L Claire Gay, Silvia Carnaccini, Brittany Seibert, Lucas M Ferreri, Ginger Geiger, Algimantas Jasinskas, Rie Nakajima, Daniela S Rajao, Irina Isakova-Sivak, Larisa Rudenko, Amy L Vincent, D Huw Davies, Daniel R Perez

Journal: Vaccines (Basel)

PubMed ID: 34198994

Doi: 10.3390/vaccines9070703

Products & Services: Gene Synthesis

Cell free protein synthesis versus yeast expression - A comparison using insulin as a model protein

Authors: Astrid B Jensen, Franta Hubálek, Carsten Enggaard Stidsen, Eva Johansson, Fredrik Kryh Öberg, Michael Skjøt, Thomas Kjeldsen

Journal: Protein Expr Purif

PubMed ID: 34089870

Doi: 10.1016/j.pep.2021.105910

Products & Services: Proteins, Expression, Isolation and Analysis

TPX-0131, a Potent CNS-Penetrant, Next-Generation Inhibitor of Wild-Type ALK and ALK-Resistant Mutations

Authors: Brion W Murray, Dayong Zhai, Wei Deng, Xin Zhang, Jane Ung, Vivian Nguyen, Han Zhang, Maria Barrera, Ana Parra, Jessica Cowell, Dong J Lee, Herve Aloysius, Evan Rogers

Journal: Mol Cancer Ther

PubMed ID: 34158340

Doi: 10.1158/1535-7163.MCT-21-0221

Products & Services: Plasmid DNA Preparation

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