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DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α
Authors: Aidi Gao, Mingxia Zhang, Shuang Qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao
Journal: Cell Death Dis
PubMed ID: 38402183
Doi: 10.1038/s41419-024-06552-6
Products & Services: Proteins, Expression, Isolation and Analysis   
Characterization of N-glycosylation and its Functional Role in SIDT1-Mediated RNA Uptake
Authors: Tingting Yang, Haonan Xiao, Xiulan Chen, Le Zheng, Hangtian Guo, Jiaqi Wang, Xiaohong Jiang, Chen-Yu Zhang, Fuquan Yang, Xiaoyun Ji
Journal: J Biol Chem
PubMed ID: 38237680
Doi: 10.1016/j.jbc.2024.105654
Products & Services: Synthetic sgRNA and crRNA Service   
The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression
Authors: Qiankun Wang, Kolin M Clark, Ritudhwaj Tiwari, Nagarajan Raju, Gregory K Tharp, Jeffrey Rogers, R Alan Harris, Muthuswamy Raveendran, Steven E Bosinger, Tricia H Burdo, Guido Silvestri, Liang Shan
Journal: Cell
PubMed ID: 38428396
Doi: 10.1016/j.cell.2024.01.048
Products & Services: Gene Synthesis   
The CRL5–SPSB3 ubiquitin ligase targets nuclear cGAS for degradation
Authors: Pengbiao Xu , Ying Liu , Chong Liu , Baptiste Guey , Lingyun Li , Pauline Melenec , Jonathan Ricci , Andrea Ablasser 
Journal: Nature
PubMed ID: 38418882
Doi: 10.1038/s41586-024-07112-w
Products & Services: Antibody Modification and Purification Services   
Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes
Authors: Filip Mihalič, Dahiana Arcila, Mats E Pettersson, Pouria Farkhondehkish, Eva Andersson, Leif Andersson, Ricardo Betancur-R, Per Jemth
Journal: Mol Biol Evol
PubMed ID: 38301272
Doi: 10.1093/molbev/msae018
Products & Services: Proteins, Expression, Isolation and Analysis   
Tandem repeats of highly bioluminescent NanoLuc are refolded noncanonically by the Hsp70 machinery
Authors: Dimitra Apostolidou, Pan Zhang, Devanshi Pandya, Kaden Bock, Qinglian Liu, Weitao Yang, Piotr E Marszalek
Journal: Protein Sci
PubMed ID: 38284490
Doi: 10.1002/pro.4895
Products & Services: Custom Vector Construction   
Chagasin from Trypanosoma cruzi as a molecular scaffold to express epitopes of TSA-1 as soluble recombinant chimeras
Authors: Rosa Elena Cárdenas-Guerra, Octavio Montes-Flores, Edgar Ezequiel Nava-Pintor, Gerardo Reséndiz-Cardiel, Claudia Ivonne Flores-Pucheta, Yasmín Irene Rodríguez-Gavaldón, Rossana Arroyo, Maria Elena Bottazzi, Peter J Hotez, Jaime Ortega-López
Journal: Protein Expr Purif
PubMed ID: 38423156
Doi: 10.1016/j.pep.2024.106458
Products & Services: Codon Optimization   
Supramolecular Synthons in Protein-Ligand Frameworks
Authors: Ronan J Flood, Niamh M Mockler, Aurélien Thureau, Maura Malinska, Peter B Crowley
Journal: Cryst Growth Des
PubMed ID: 38463617
Doi: 10.1021/acs.cgd.3c01480
Products & Services: Molecular Biology Reagents   
A mutational atlas for Parkin proteostasis
Authors: Lene Clausen, Vasileios Voutsinos, Matteo Cagiada, Kristoffer E Johansson, Martin Grønbæk-Thygesen, Snehal Nariya, Rachel L Powell, Magnus K N Have, Vibe H Oestergaard, Amelie Stein, Douglas M Fowler, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen
Journal: Nat Commun
PubMed ID: 38378758
Doi: 10.1038/s41467-024-45829-4
Products & Services: Mutagenesis Services   
Constitutive activation mechanism of a class C GPCR
Authors: Jinwoo Shin, Junhyeon Park, Jieun Jeong, Jordy Homing Lam, Xingyu Qiu, Di Wu, Kuglae Kim, Joo-Youn Lee, Carol V Robinson, Jaekyung Hyun, Vsevolod Katritch, Kwang Pyo Kim, Yunje Cho
Journal: Nat Struct Mol Biol
PubMed ID: 38332368
Doi: 10.1038/s41594-024-01224-7
Products & Services: Proteins, Expression, Isolation and Analysis