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The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+-mediated signaling via retinoic acid regulation of Rcan2 and Kcnk5b

Authors: Xiaowen Jiang, Kun Zhao, Yi Sun, Xinyue Song, Chao Yi, Tianlong Xiong, Sen Wang, Yi Yu, Xiduo Chen, Run Liu, Xin Yan, Christopher L Antos

Journal: PLoS Biol

PubMed ID: 38527087

Doi: journal.pbio.3002565

Products & Services: GenCrispr Cas9 Genome Editing

Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs

Authors: James Jiqi Wang, Sanshan Jin, Heng Zhang, Youwei Xu, Wen Hu, Yi Jiang, Chen Chen, Dao Wen Wang, H Eric Xu, Canrong Wu

Journal: Sci Adv .

PubMed ID: 38335293

Doi: 10.1126/sciadv.adk5184

Products & Services: Proteins, Expression, Isolation and Analysis

SRRM2 phase separation drives assembly of nuclear speckle subcompartments

Authors: Mengjun Zhang, Zhuang Gu, Shuanghui Guo, Yingtian Sun, Suibin Ma, Shuo Yang, Jierui Guo, Chenxi Fang, Li Shu, Yifan Ge, Zhongwen Chen, Bo Wang

Journal: Cell Rep .

PubMed ID: 38381607

Doi: 10.1016/j.celrep.2024.113827

Products & Services: Proteins, Expression, Isolation and Analysis

N-homocysteinylation of DJ-1 promotes neurodegeneration in Parkinson's disease

Authors: Tao Guo, Lingyan Zhou, Min Xiong, Jing Xiong, Juan Huang, Yiming Li, Guoxin Zhang, Guiqin Chen, Zhi-Hao Wang, Tingting Xiao, Dan Hu, Anyu Bao, Zhentao Zhang

Journal: Aging Cell

PubMed ID: 38380563

Doi: 10.1111/acel.14124

Products & Services: Proteins, Expression, Isolation and Analysis

Mitochondrial amidoxime-reducing component 1 p.Ala165Thr increases protein degradation mediated by the proteasome

Authors: Tanmoy Dutta, Kavitha Sasidharan, Ester Ciociola, Grazia Pennisi, Francesca R Noto, Lohitesh Kovooru, Tobias Kroon, Anna Lindblom, Yue Du, Mohammad Pirmoradian, Simonetta Wallin, Rosellina M Mancina, Daniel Lindén, Stefano Romeo

Journal: Liver Int

PubMed ID: 38375985

Doi: 10.1111/liv.15857

Products & Services: Mutagenesis Services

Borrelia miyamotoi BipA-like protein, BipM, is a candidate serodiagnostic antigen distinguishing between Lyme disease and relapsing fever Borrelia infections

Authors: Kevin S Brandt, Brittany A Armstrong, Irina Goodrich, Robert D Gilmore

Journal: Ticks Tick Borne Dis

PubMed ID: 38367587

Doi: 10.1016/j.ttbdis.2024.102324

Products & Services: Recombinant Proteins

AbImmPred: An immunogenicity prediction method for therapeutic antibodies using AntiBERTy-based sequence features

Authors: Hong Wang, Xiaohu Hao, Yuzhuo He, Long Fan

Journal: PLoS ONE

PubMed ID: 38394128

Doi: 10.1371/journal.pone.0296737

Products & Services: Proteins, Expression, Isolation and Analysis

Autoinhibition and activation of myosin VI revealed by its cryo-EM structure

Authors: Fengfeng Niu, Lingxuan Li, Lei Wang, Jinman Xiao, Shun Xu, Yong Liu, Leishu Lin, Cong Yu, Zhiyi Wei

Journal: Nat Commun

PubMed ID: 38331992

Doi: 10.1038/s41467-024-45424-7

Products & Services: Proteins, Expression, Isolation and Analysis

Enhancing CAR Macrophage Efferocytosis Via Surface Engineered Lipid Nanoparticles Targeting LXR Signaling

Authors: Skylar T Chuang, Joshua B Stein, Sarah Nevins, Cemile Kilic Bektas, Hye Kyu Choi, Wan-Kyu Ko, Hyunjun Jang, Jihun Ha, Ki-Bum Lee

Journal: Adv Mater

PubMed ID: 38353580

Doi: 10.1002/adma.202308377

Products & Services: Proteins, Expression, Isolation and Analysis

Cutting Edge: Characterization of Low Copy Number Human Angiotensin-Converting Enzyme 2-Transgenic Mice as an Improved Model of SARS-CoV-2 Infection

Authors: Christine M Bradshaw, Teodora Georgieva, Trevor N Tankersley, Tama Taylor-Doyle, Larry Johnson, Jennifer L Uhrlaub, David Besselsen, Janko Ž Nikolich

Journal: J Immunol

PubMed ID: 38197714

Doi: 10.4049/jimmunol.2300591

Products & Services: Proteins, Expression, Isolation and Analysis

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