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A Single-Domain TCR-like Antibody Selective for the Qa-1/Qdm Peptide Complex Enhances Tumoricidal Activity of NK Cells via Blocking the NKG2A Immune Checkpoint

Authors: Soroush Ghaffari, Katherine Upchurch-Ange, Susanne Gimlin, Trivendra Tripathi, Marjolein Sluijter, Jim Middelburg, Thorbald van Hall, Jon Weidanz

Journal: J Immunol

PubMed ID: 35418467

Doi: 10.4049/jimmunol.2100790

Products & Services: Protein and Antibody Isolation

A Novel Multi-Epitope Edible Vaccine Candidate for Newcastle Disease Virus: Approach

Authors: Atena Mozafari, Jafar Amani, Shahla Shahsavandi, Ali Hatef Salmanian

Journal: Iran J Biotechnol

PubMed ID: 36337069

Doi: 10.30498/ijb.2022.298822.3119

Products & Services: Molecular Biology Tools

Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine

Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35149556

Doi: 10.1073/pnas.2119995119

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A TCR mimic monoclonal antibody reactive with the "public" phospho-neoantigen pIRS2/HLA-A*02:01 complex

Authors: Tao Dao, Sung Soo Mun, Zaki Molvi, Tatyana Korontsvit, Martin G Klatt, Abdul G Khan, Elisabeth K Nyakatura, Mary Ann Pohl, Thomas E White, Paul J Balderes, Ivo C Lorenz, Richard J O'Reilly, David A Scheinberg

Journal: JCI Insight

PubMed ID: 35260532

Doi: 10.1172/jci.insight.151624

Products & Services: Catalog Antibodies

Abrogation of self-tolerance by misfolded self-antigens complexed with MHC class II molecules

Authors: Hui Jin, Kazuki Kishida, Noriko Arase, Sumiko Matsuoka, Wataru Nakai, Masako Kohyama, Tadahiro Suenaga, Ken Yamamoto, Takehiko Sasazuki, Hisashi Arase

Journal: Sci Adv

PubMed ID: 35245125

Doi: 10.1126/sciadv.abj9867

Products & Services: Peptide Synthesis

An In Vivo Screen to Identify Short Peptide Mimotopes with Enhanced Antitumor Immunogenicity

Authors: Xuedan He, Shiqi Zhou, Breandan Quinn, Dushyant Jahagirdar, Joaquin Ortega, Mark D Long, Scott I Abrams, Jonathan F Lovell

Journal: Cancer Immunol Res

PubMed ID: 34992135

Doi: 10.1158/2326-6066.CIR-21-0332

Products & Services: Peptide Synthesis

KIR3DL05 and KIR3DS02 Recognition of a Nonclassical MHC Class I Molecule in the Rhesus Macaque Implicated in Pregnancy Success

Authors: Rachel E Nicholas, Kjell Sandstrom, Jennifer L Anderson, Willow R Smith, Molly Wetzel, Priyankana Banerjee, Sanath Kumar Janaka, David T Evans

Journal: Front Immunol

PubMed ID: 35401580

Doi: 10.3389/fimmu.2022.841136

Products & Services: Custom Vector Construction

T cell receptors employ diverse strategies to target a p53 cancer neoantigen

Authors: Daichao Wu, Ragul Gowathaman, Brian G Pierce, Roy A Mariuzza

Journal: J Biol Chem

PubMed ID: 35124005

Doi: 10.1016/j.jbc.2022.101684

Products & Services: Custom Vector Construction

In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles

Authors: Fang-Yi Su, Qingyang Henry Zhao, Shreyas N Dahotre, Lena Gamboa, Swapnil Subhash Bawage, Aaron D Silva Trenkle, Ali Zamat, Hathaichanok Phuengkham, Rafi Ahmed, Philip J Santangelo, Gabriel A Kwong

Journal: Sci Adv

PubMed ID: 35196075

Doi: 10.1126/sciadv.abm7950

Products & Services: Catalog Antibodies

Aluminum nanoparticles deliver a dual-epitope peptide for enhanced anti-tumor immunotherapy

Authors: Shuting Bai, Hao Jiang, Yuanshuai Song, Yining Zhu, Ming Qin, Chunting He, Guangsheng Du, Xun Sun

Journal: J Control Release

PubMed ID: 35217098

Doi: 10.1016/j.jconrel.2022.02.027

Products & Services: Endotoxin Detection & Removal System

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