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BARD1 serum autoantibodies for the detection of lung cancer.

PLoS ONE. 2017; 
Pilyugin Maxim,Descloux Pascaline,André Pierre-Alain,Laszlo Viktoria,Dome Balazs,Hegedus Balazs,Sardy Sylvain,Janes Samuel,Bianco Andrea,Laurent Geoffrey J,Irminger-Finger Irm
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摘要

Currently the screening for lung cancer for risk groups is based on Computed Tomography (CT) or low dose CT (LDCT); however, the lung cancer death rate has not decreased significantly with people undergoing LDCT. We aimed to develop a simple reliable blood test for early detection of all types of lung cancer based on the immunogenicity of aberrant forms of BARD1 that are specifically upregulated in lung cancer.

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