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Characterization of a computationally designed water-soluble human μ-opioid receptor variant using available structural information.

Anesthesiology. 2014;

Zhao Xuelian，Perez-Aguilar Jose Manuel，Matsunaga Felipe，Lerner Mitchell，Xi Jin，Selling Bernard，Johnson A T Charlie，Saven Jeffery G，Liu R

Products/Services Used	Details	Operation
Custom Vector Construction	The synthetic complementary deoxyribonucleotide encoding of the wsMUR-TM (previous version reported)7 and wsMUR-TM_v2 (the modified new version) was constructed by DNA2.0 Inc. (Menlo Park, CA) and GenScript Inc. (Piscataway, NJ), respectively.	Get A Quote

摘要

The recent X-ray crystal structure of the murine μ-opioid receptor (MUR) allowed the authors to reengineer a previously designed water-soluble variant of the transmembrane portion of the human MUR (wsMUR-TM).