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Chemokine Receptor 7 is Essential for Coxiella burnetii Whole-Cell Vaccine Induced Cellular Immunity but Dispensable for Vaccine Mediated Protective Immunity.

J. Infect. Dis.. 2019;

ChenChen，van SchaikErin J，GregoryAnthony E，VigilAdam，FelgnerPhillip L，HendrixLaura R，SamuelJam

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摘要

Protective immunity against Coxiella burnetii infection is conferred by vaccination with virulent (PI-WCV)， but not avirulent (PII-WCV) whole-cell inactivated bacterium. The only well characterized antigenic difference between virulent and avirulent C. burnetii is they have smooth and rough LPS respectively.