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MicroRNA-124 regulates cardiomyocyte apoptosis and myocardial infarction through targeting Dhcr24.

J. Mol. Cell. Cardiol.. 2019;

HanFei，ChenQishan，SuJia，ZhengAncheng，ChenKai，SunShasha，WuHong，JiangLiujun，XuXiaolei，YangMei，YangFeng，ZhuJianhua，Zha

Products/Services Used	Details	Operation
Custom Vector Construction	In ad- dition, miR-124 mimic, Dhcr24 3′UTR plasmid, Dhcr24 over-expression plasmid vectors (GenScript) as well as the negative controls (mimic ctrl and pcDNA3.... Dual-luciferase reporter assays Dhcr24 3′UTR were cloned into the pEZX-MT06 vector (Genscript) and target site mutations were obtained (Genscript).	Get A Quote

摘要

microRNA-124(miR-124) has recently been reported to be elevated in cardiovascular disease. In this study， we aimed to investigate the exact role of miR-124 in cardiomyocytes and myocardial infarction， identifying the functional target and its regulatory mechanisms.