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A cis-eQTL genetic variant in PLK4 confers high risk of hepatocellular carcinoma.

Cancer Med. 2019;

Meng Lijuan，Zhou Yan，Ju Sihan，Han Jing，Song Ci，Kong Jing，Wu Yifei，Lu Shuai，Xu Jiani，Yuan Wenwen，Zhang Erbao，Wang Cheng，Hu Zhibin，Gu Yayun，Luo Rongcheng，Wang Xu

Products/Services Used	Details	Operation
Molecular Biology Reagents	PLK4 plasmids were purchased in Genscript Technologies (Genscript, China).	Get A Quote

摘要

The overexpression and knockdown of PLK4 were both reported to generate aneuploidy. Thus， we aimed to investigate whether genetic variants in PLK4 contribute to the development of hepatocellular carcinoma (HCC).