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Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins.

J. Infect. Dis.. 2017; 
Gubareva Larisa V,Sleeman Katrina,Guo Zhu,Yang Hua,Hodges Erin,Davis Charles T,Baranovich Tatiana,Stevens J
Products/Services Used Details Operation
Custom Vector Construction (GenScript) and subcloned into a pIEx-4 vector (EMD Millipore), using the In-Fusion HD cloning system Get A Quote

摘要

Neuraminidase (NA) inhibitors are the recommended antiviral medications for influenza treatment. However, their therapeutic efficacy can be compromised by NA changes that emerge naturally and/or following antiviral treatment. Knowledge of which molecular changes confer drug resistance of influenza A(H7N9) viruses (group 2NA) remains sparse.

关键词

A(H7N9),Neuraminidase,bird flu,drug resistance,recombinant pro