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Drug Susceptibility Evaluation of an Influenza A(H7N9) Virus by Analyzing Recombinant Neuraminidase Proteins.

J. Infect. Dis.. 2017;

Gubareva Larisa V，Sleeman Katrina，Guo Zhu，Yang Hua，Hodges Erin，Davis Charles T，Baranovich Tatiana，Stevens J

Products/Services Used	Details	Operation
Custom Vector Construction	(GenScript) and subcloned into a pIEx-4 vector (EMD Millipore), using the In-Fusion HD cloning system	Get A Quote

摘要

Neuraminidase (NA) inhibitors are the recommended antiviral medications for influenza treatment. However， their therapeutic efficacy can be compromised by NA changes that emerge naturally and/or following antiviral treatment. Knowledge of which molecular changes confer drug resistance of influenza A(H7N9) viruses (group 2NA) remains sparse.