至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

A Peptide Signaling System that Rapidly Enforces Paternity in the Aedes aegypti Mosquito.

Curr. Biol.. 2017; 
Duvall Laura B,Basrur Nipun S,Molina Henrik,McMeniman Conor J,Vosshall Lesl
Products/Services Used Details Operation
Custom Vector Construction by GenScript and subcloned into the XhoI-NotI sites of the pME18s vector for trans- fection and expression Get A Quote

摘要

Female Aedes aegypti mosquitoes typically mate only once with one male in their lifetime, a behavior known as "monandry" [1]. This single mating event provisions the female with sufficient sperm to fertilize the >500 eggs she will produce during her ~4- to 6-week lifespan in the laboratory [2]. Successful mating induces lifetime refractoriness to subsequent insemination by other males, enforcing the paternity of the first male [3-5]. Ae. aegypti mate in flight near human hosts [6], and females become refractory to remating within seconds [1, 3, 4], suggesting the existence of a rapid mechanism to prevent female remating. In this study, we implicate HP-I, an Aedes- and male-specific peptide tra... More

关键词

Aedes aegypti mosquito,Head Peptide-I,male seminal fluid proteins,mating behavior,paternity enforcement,peptides,satyriza