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YTHDC1 mediates nuclear export of N-methyladenosine methylated mRNAs.

Elife. 2017; 
Roundtree Ian A,Luo Guan-Zheng,Zhang Zijie,Wang Xiao,Zhou Tao,Cui Yiquang,Sha Jiahao,Huang Xingxu,Guerrero Laura,Xie Phil,He Emily,Shen Bin,He C
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摘要

-methyladenosine (mA) is the most abundant internal modification of eukaryotic messenger RNA (mRNA) and plays critical roles in RNA biology. The function of this modification is mediated by mA-selective 'reader' proteins of the YTH family, which incorpora

关键词

RNA modification,RNA processing,biochemistry,cell biology,gene regulation,human,mRNA ex