Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanum tuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal and antibacterial activity. Most attempts to produce StSN1， or homologous peptides， in a soluble native state using bacterial， yeast or synthetic expression systems have presented production bottlenecks such as insolubility， misfolding or low yields.
Snakin-1 (StSN1) is a broad-spectrum antimicrobial cysteine-rich peptide isolated from Solanum tuberosum. Its biotechnological potential has been already recognized since it exhibits in vivo antifungal and antibacterial activity. Most attempts to produce StSN1， or homologous peptides， in a soluble native state using bacterial， yeast or synthetic expression systems have presented production bottlenecks such as insolubility， misfolding or low yields.
