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An unfolded variant of the major peanut allergen Ara h 2 with decreased anaphylactic potential.

Clin. Exp. Allergy. 2012; 
StarklP,FelixF,KrishnamurthyD,StremnitzerC,Roth-WalterF,PrickettS R,VoskampA L,WillensdorferA,SzalaiK,WeichselbaumerM,O'HehirR E,Jensen-Jaro
Products/Services Used Details Operation
Peptide Synthesis … A detailed protocol can be found in the Material and methods section of the online supplement. Ara h 2 peptides (GenScript USA Inc., Piscataway, NJ, USA) were prepared to > 90% purity, reconstituted at 2 mg/ml in PBS and stored in aliquots at −80°C until use … Get A Quote

摘要

Peanut allergy causes severe type 1 hypersensitivity reactions and conventional immunotherapy against peanut allergy is associated with a high risk of anaphylaxis.

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