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WT1 promotes invasion of NSCLC via suppression of CDH1.

J Thorac Oncol. 2013;

WuChen，ZhuWeiyou，QianJing，HeShaohua，WuChangping，ChenYijiang，ShuYong

Products/Services Used	Details	Operation
Plasmid DNA Preparation	WT1 gene was synthesized (purchased from GenScript, Nanjing, China) with restrictive digestion site of MluI in both ends, subcloned into pLV-GFP plasmid (gifted by Prof. Beicheng Sun, University of Nanjing Medical University, China), and named pLV-GFP-WT1.	Get A Quote

摘要

The Wilms' tumor gene (WT1) has been identified as an oncogene in many malignant diseases， and aberrant WT1 expression has been linked to development， progression， and prognosis of non-small-cell lung cancer (NSCLC). We sought to investigate the underlying mechanism of WT1 and metastasis in NSCLC.