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Aberrant reduction of MiR-141 increased CD47/CUL3 in Hirschsprung's disease.

Cell. Physiol. Biochem.. 2013;

TangWeibing，QinJingjing，TangJunwei，ZhangHongwei，ZhouZhigang，LiBo，GengQiming，WuWei，XiaYankai，XuXia

Products/Services Used	Details	Operation
Custom Vector Construction	The 3’-UTR sequence of CD47 and CUL3 predicted to interact with miR-141 and the mutated sequence were inserted into the KpnI and SacI sites of pGL3 promoter vector (Genscript, Nanjing, China).	Get A Quote

摘要

MiR-141 has been confirmed to be associated with various human diseases. However， whether miR-141 is involved in the pathogenesis of Hirschsprung's disease (HSCR) remains unknown. Here， we design the experiment to reveal the relationship between miR-141 and HSCR.