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Generation and characterization of a monoclonal antibody against human BCL6 for immunohistochemical diagnosis.

PLoS ONE. 2019-01; 
JiaKunzhi,ZhangDanping,WangYanghai,LiuYaju,KongXiangzhu,YangQinghai,ChenHuiling,XieChengjie,WangSh
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Gene Synthesis The optimized coding DNA for BCL61-350 was synthesized by Nanjing Genscript Biotech Co., Ltd (Nanjing, China). Get A Quote

摘要

Human B-cell lymphoma 6 (BCL6) gene, usually coding protein of 706 amino acids, is closely associated with large B cell lymphoma. Researches showed that protein mutation or change of expression levels usually happened in the mounting non-hodgkin lymphoma (NHL). Thus BCL6 is considered to be involved in germinal center (GC)-derived lymphoma.

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