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MiR-3174 functions as an oncogene in rectal cancer by targeting PCBD2.

Eur Rev Med Pharmacol Sci. 2019;

ZhangD-L，Y

Products/Services Used	Details	Operation
Custom Vector Construction	we considered that PCBD2 might be a direct down-stream target of miR-3174. Luciferase Report Gene Assay Wild-type PCBD2 3'-UTR sequence or the mutant PCBD2 3'-UTR sequence was combined with pGL3 promoter vector (Genscript	Get A Quote

摘要

Colorectal cancer (CRC) is one of the most frequent malignant tumors worldwide. Colon cancer and rectal cancer are two different malignant types， and it is important to distinguish these two cancers. However， the physiological function of microRNA-3174 (miR-3174) in rectal cancer remains unknown. Therefore， the aim of this study was to investigate the role of miR-3174 in rectal cancer progression and to explore the possible underlying mechanism.