| Products/Services Used | Details | Operation |
|---|---|---|
| Custom Vector Construction | … GenePharm (Shanghai, China). Expression vector (pcDNA3.1+) containing the open reading frame of magnesium transporter 1 (MAGT1) and the empty vector were purchased from GenScript (Nanjing, China). Transfection was … | Get A Quote |
microRNAs (miRNAs) can function as a tumor suppressor or oncogenic genes in human cancers. Alternation expression of miR-199a-5p has been revealed in several human cancers. However， its expression pattern and biological roles in glioma remain unclear. Expression levels of miR-199a-5p in glioma were evaluated at first. The effects of miR-199a-5p expression on cell proliferation， migration， and invasion were investigated using the MTT assay， wound-healing assay， and transwell invasion assay. The expression of miR-199a-5p was found to be reduced in glioma cell lines. Overexpression of miR-199a-5p inhibits glioma cell proliferation， migration， and invasion in vitro. Furthermore， the target of miR-19... More
