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Using Genetic Buffering Relationships Identified in Fission Yeast to Elucidate the Molecular Pathology of Tuberous Sclerosis

Biology Open 2018. 2018;

Ashyad Rayhan, Adam Faller, Ryan Chevalier, Alannah Mattice, Jim Karagiannis

Products/Services Used	Details	Operation
Plasmid DNA Preparation	… Predicted Completion Date: September 30th, 2014 Progress: As part of the service provided by Genscript, it was possible to have the synthetic sequences cloned directly into the pAW8X “exchange” plasmids upon synthesis Status: Complete …	Get A Quote

摘要

Tuberous sclerosis complex is an autosomal dominant disorder characterized by benign tumors arising from the abnormal activation of mTOR signaling in cells lacking TSC1 (hamartin) or TSC2 (tuberin) activity.