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T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy.

Clin. Exp. Allergy. 2016-03; 
WaiC Y Y,LeungN Y H,LeungP S C,Ch
Products/Services Used Details Operation
Peptide Synthesis … tropomyosin‐induced anaphylaxis. Methods. Peptide synthesis. Eighteen overlapping peptides spanning the full length of Met e 1 (Accession number Q25456.1) 30 were synthesized (GenScript, Piscataway, NJ, USA). Each peptide … Get A Quote

摘要

Shellfish allergy is one of the most common food hypersensitivities worldwide but allergen-specific immunotherapy for shellfish allergy is not yet available. We believe that T cell peptide-based immunotherapy holds the potential for modulating allergic responses without IgE cross-linking.

关键词

Met e 1,T cell epitopes,Th1/Th2 balance,allergen-specific immunotherapy,peptide immunotherapy,peripheral tolerance,shell