| Products/Services Used | Details | Operation |
|---|---|---|
| DNA Sequencing | … The PCR parameters for the gB gene were: 95 °C for 5 min, 30 cycles of 94 °C for 60 s, 55 °C for 60 s, and 72 °C for 2 min, and then 72 °C for 10 min The PCR products were separated on a 1 % DNA gel and then sequenced by Genscript (Nanjing, China) … | Get A Quote |
Cell movement has essential functions in development， immunity， and cancer. Various cell migration patterns have been reported， but no general rule has emerged so far. Here， we show on the basis of experimental data in vitro and in vivo that cell persistence， which quantifies the straightness of trajectories， is robustly coupled to cell migration speed. We suggest that this universal coupling constitutes a generic law of cell migration， which originates in the advection of polarity cues by an actin cytoskeleton undergoing flows at the cellular scale. Our analysis relies on a theoretical model that we validate by measuring the persistence of cells upon modulation of actin flow speeds and upon optog... More
