资源 » 参考数据库 » 客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

Urate crystals induce NLRP3 inflammasome-dependent IL-1β secretion and proliferation in isolated primary human T-cells.

Hippokratia. 2015;

EleftheriadisT，PissasG，AntoniadiG，MakriP，LiakopoulosV，Stefani

Products/Services Used	Details	Operation
Peptide Synthesis	… They were left at room temperature with constant stirring for 1 h Then washed with DMF, water, ethanol, and acetone, then dried, and stored in a desiccator until the adhesion of biomolecules Peptide immobilization The peptides used for the study were provided by GenScript …	Get A Quote

摘要

Urate through NOD-like receptor family， pyrin domain containing 3 (NLRP3) inflammasome-dependent caspase-1 activation stimulates macrophages to secrete inteleukin-1β (IL-1β). Urate also enhances adaptive immunity indirectly through its effect on antigen presenting cells. In this study， the direct effect of urate on isolated primary human T-cells was evaluated.