| Products/Services Used | Details | Operation |
|---|---|---|
| Peptide Synthesis | … Xu6–FLAG, the conjugate of the peroxidase sequence Xu6 and the molecular recognition sequence FLAG, was synthesized by GenScript USA Inc Table 1 Peptide sequences prepared by standard Fmoc solid-phase synthesis Peptide, Sequence Xu1, YRLPHVVAPG … | Get A Quote |
When minimal functional sequences are used， it is possible to integrate multiple functions on a single peptide chain， like a "single stroke drawing". Here a dual functional peptide was designed by combining in vitro selected catalytic and binding activities. For catalytic activity， we performed in vitro selection for a peptide aptamer binding to hemin by using ribosome display and isolated a peptide that had peroxidase activity in the presence of hemin. By combining the selected catalytic peptide with a peptide antigen， which can be recognized by an antibody， an enzyme-antibody conjugate-like peptide was obtained. This study demonstrates a successful strategy to create dual functionalized peptide chai... More
