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Upregulation of miR-504-3p is associated with favorable prognosis of acute myeloid leukemia and may serve as a tumor suppressor by targeting MTHFD2.

Eur Rev Med Pharmacol Sci. 2019;

LiS-M，ZhaoY-Q，HaoY-L，Lian

Products/Services Used	Details	Operation
Catalog Peptides	… The miRNA mimics including miR-504- 3p mimic, negative control mimic (NC-mim- ic) were purchased from Genscript Co., Ltd … Bio, Taicang, Jiang- su, China), the miRNA mimics or siRNAs were transfected using Lipofectamine 3000 reagents (Invitrogen, Carlsbad, CA, USA) …	Get A Quote

摘要

Deregulated expression of miRNAs contributes to the development of acute myeloid leukemia (AML). miR-504-3p， one of these miRNAs， has been found have upregulated expression in various human malignancies. Our present study aimed to detect the expression of miR-504-3p and its biological effect in AML.