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Sorting tubules regulate blood-brain barrier transcytosis

Cell Reports. 2017; 
Roberto Villasen˜ or, Michael Schilling, Janani Sundaresan, Yves Lutz, Ludovic Collin
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Gene Synthesis Gene synthesis, mutagenesis, cloning, and plasmid purification were performed by Genscript. Primary mouse BECs were acquired from Cell Biologics and used at passage number 4, following the manufacturer’s instructions. Get A Quote

摘要

Highlights d Quantitative analysis of intracellular transport in brain endothelial cells d Rab17 overexpression alters tubule dynamics in brain endothelial cells d Manipulating tubule dynamics induces transcytosis in brain endothelial cells d Intracellular tubules mediate receptor transcytosis across the blood-brain barrier

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