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Twelve-year survival and immune correlates in dendritic cell-vaccinated melanoma patients.

JCI Insight. 2017; 
GrossStefanie,ErdmannMichael,HaendleIna,VolandSteve,BergerThomas,SchultzErwin,StrasserErwin,DankerlPeter,JankaRolf,SchliepStefan,HeinzerlingLucie,SotlarKarl,CouliePierre,SchulerGerold,Schuler-ThurnerBeat
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Peptide Synthesis PHA (Phytohaemagglutinin) amd SEA (Staphylococcal Enterotoxin A) were both from Sigma, viral peptides were from Genscript. Get A Quote

摘要

Reports on long-term (≥10 years) effects of cancer vaccines are missing. Therefore, in 2002, we initiated a phase I/II trial in cutaneous melanoma patients to further explore the immunogenicity of our DC vaccine and to establish its long-term toxicity and clinical benefit after a planned 10-year followup.

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