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MiR-1-5p is down-regulated in gallbladder carcinoma and suppresses cell proliferation, migration and invasion by targeting Notch2.

Pathol. Res. Pract.. 2019-01; 
HuaChun Bo, SongSheng Bo, MaHui Li, LiXi
Products/Services Used Details Operation
Gene Synthesis … 2.10. Luciferase reporter analysis. Wilde type of Notch2 3′-UTR sites (WT) or the mutant sites of Notch2 3′-UTR (MUT) was inserted into a firefly luciferase reporter vector, pGL3 promoter vector (Genscript, Nanjing, Jiangsu, China) … Get A Quote

摘要

Numerous studies have demonstrated that aberrant microRNAs (miRNAs) are involved in tumorigenesis and tumor progression. Nevertheless, the precise role of miR-1-5p in gallbladder carcinoma cell growth and metastasis remains not fully revealed.

关键词

Gallbladder carcinoma,Invasion,MiR-1-5p,Migration,No