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MiR-198 affects the proliferation and apoptosis of colorectal cancer through regulation of ADAM28/JAK-STAT signaling pathway.

Eur Rev Med Pharmacol Sci. 2019-03; 
LiL-X, LamI-H, LiangF-F, YiS-P, YeL-F, WangJ-T, GuoW-W
Products/Services Used Details Operation
Gene Synthesis … Genechem (Shanghai, China). An ADAM28 expression vec- tor with its open reading frame inserted into pcD- NA3.1 plasmid (ADAM28-vector) and a NC-vec- tor was purchased from GenScript (Nanjing, China). Cell transfection was … Get A Quote

摘要

Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. microRNA-198 (miR-198) was reported to be a tumor suppressive miRNA but its role in CRC is largely unknown. Thus, we aimed to investigate the role of miR-198 and its downstream signaling pathway in CRC.

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