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MiR-610 functions as a tumor suppressor in oral squamous cell carcinoma by directly targeting AGK.

Eur Rev Med Pharmacol Sci. 2019-01;

YaoL-X, LiuJ

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Gene Synthesis	… The cells were cul- tured at 37°C with 5% CO2. The negative control mimic (control mimic) and miR-610 mimic were all purchased from GenScript Co., Ltd. (Nanjing, Jiangsu, China). The cDNA of AKG was sub- cloned into pcDNA3.1 vector by FitGene Co., Ltd …	Get A Quote

摘要

MicroRNA-610 (miR-610) functions as a tumor suppressor in various types of cancers. However， whether miR-610 acted as a functional miRNA in oral squamous cell carcinoma (OSCC) is still largely unknown. The current study was designed to explore the expression pattern and function of miR-610 in OSCC and to investigate the possible molecular mechanisms.