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KCNMA1 cooperating with PTK2 is a novel tumor suppressor in gastric cancer and is associated with disease outcome

Mol. Cancer. 2017-02; 
MaGaoxiang, LiuHanting, HuaQiuhan, WangMeilin, DuMulong, LinYadi, GeYuqiu, GongWeida, ZhaoQinghong, QiangFulin, TaoGuoquan, ZhangZhengdong, ChuHa
Products/Services Used Details Operation
Gene Synthesis … Construction of KCNMA1 expression plasmid and RNA interference. The full-length open reading frame sequence of KCNMA1 was constructed by GenScript USA Inc. (Nanjing, China) and then was subcloned into the mammalian expression vector pIRES-EGFP … Get A Quote

摘要

Inactivation of tumor suppressor genes by promoter hypermethylation plays a key role in the tumorgenesis. It is necessary to uncover the detailed pattern of whole genome-wide abnormal DNA methylation during the development of gastric cancer (GC).

关键词

Gastric cancer,KCNMA1 Methylation,Progn