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Calprotectin protects against experimental colonic inflammation in mice.

Br. J. Pharmacol.. 2018-10;

ArandaCarlos J，OcónBorja，Arredondo-AmadorMaría，SuárezMaría Dolores，ZarzueloAntonio，ChazinWalter J，Martínez-AugustinOlga，Sánchez de MedinaFer

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Proteins, Expression, Isolation and Analysis	… verified by electrospray mass spectrometry. Lipopolysaccharides were removed using the ToxinEraserTM Endotoxin Removal Kit (Genscript) following the manufacturers instructions. Induction of DSS colitis and experimental design …	Get A Quote

摘要

Calprotectin is a heterodimer composed of two myeloid-related proteins， S100A8 and S100A9， that is abundant in neutrophils and monocytes/macrophages. Faecal levels of calprotectin are used routinely to monitor inflammatory bowel disease activity.