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Resolvin D1 attenuates imiquimod-induced mice psoriasiform dermatitis through MAPKs and NF-κB pathways.

J. Dermatol. Sci.. 2018-02; 
XuJuntao,DuanXiaoru,HuFeng,PoorunDevesh,LiuXinxin,WangXin,ZhangSong,GanLu,HeMengwen,ZhuKe,MingZhangyin,ChenHongx
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Proteins, Expression, Isolation and Analysis … The sequences were selected from Primer bank database and are listed in Table 1, the primers were purchased from GenScript Corporation. Each reaction was set up in triplicate wells … 2.9. Chemicals. Boc was obtained from GenScript Corporation … Get A Quote

摘要

Resolvin D1 (RvD1), a pro-resolution lipid mediator derived from docosahexaenoic acid (DHA), has been described to promote several kinds of inflammatory resolution. However, the effects and anti-inflammatory mechanisms of RvD1 on psoriasis have not been previously reported.

关键词

Inflammation,Keratinocyte,MAPKs,Psoriasis,Resolvi