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Forkhead box K2 inhibits the proliferation, migration, and invasion of human glioma cells and predicts a favorable prognosis.

Onco Targets Ther. 2018; 
WangBo,ZhangXueBin,WangWei,ZhuZhiZhong,TangFan,WangDong,LiuXi,ZhuangHao,YanXiao
Products/Services Used Details Operation
Proteins, Expression, Isolation and Analysis … from RiboBio (Guangzhou, China). A plasmid encoding the FOXK2 protein was purchased from Genscript (cloning ID S57120; Nanjing, China). Western blot analysis, RNA isolation, and real-time PCR. Antibodies for FOXK2 (1 … Get A Quote

摘要

Forkhead box K2 (FOXK2) is a member of the forkhead box family of transcription factors. Recently, researchers discovered that overexpression of FOXK2 inhibits the proliferation and metastasis of breast cancer, non-small cell lung cancer, and colorectal cancer, and is related to the clinical prognosis. However, in hepatocellular carcinoma, FOXK2 results in the opposite phenotypes. Currently, the contribution of FOXK2 to glioma pathogenesis is not clear.

关键词

FOXK2,Forkhead box K2,glioma,onco