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| Proteins, Expression, Isolation and Analysis | … 2B). The concentration of the purified PoIFN-δ8 was 793.6 μg/ml, while the endotoxin level of the protein was assayed using the Genscript ToxinSensor™ Chromogenic LAL Endotoxin Assay Kit (New Jersey, USA) and found to be lower than 0.01 EU/ml. Fig. 1 Fig. 1 Fig. 1 … | Get A Quote |
Foot-and-mouth disease (FMD) is one of the most devastating diseases affecting livestock. Since vaccines fail to provide protection until seven days post-vaccination， the application of anti-viral molecules is imperative for suppressing the spread of FMDV prior to development of an adaptive immune response. Interferons (IFNs) are effective for the host to fight FMDV infections; however， a novel type I IFNs， interferon delta (IFN-δ)， has not been investigated for their antiviral effects against this virus. Thus， this study investigated FMDV infection， upon pre- and post-treatment with PoIFN-δ8. Real-time quantitative PCR was used to quantify the expression levels of IFN-stimulated genes (ISGs)， i... More
