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Metabolic effects of reduced growth hormone action in fatty liver disease.

Hepatol Int. 2018-09;

RufinatschaKerstin，RessClaudia，FolieSabrina，HaasSimone，SalzmannKarin，MoserPatrizia，DobnerJochen，WeissGuenter，IruzubietaPaula，Arias-LosteMaría Teresa，CrespoJavier，TilgHerbert，KaserSus

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Proteins, Expression, Isolation and Analysis	… For designing primer and probes, the Primer Express Software (Perkin-Elmer Applied Biosystems, Warrington, US), National Center for Biotechnology Information (NCBI, Rockville Pike, US) and GenScript (GenScript, New Jersey, US) were used …	Get A Quote

摘要

Adult growth hormone (GH) deficiency is associated with fatty liver disease and shows several features of the metabolic syndrome. Vice versa obesity is characterized as a state of low GH function. Here， we aimed to define the role of hepatic GH signaling and its metabolic consequences in non-alcoholic fatty liver disease.