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ZNF70 regulates IL-1β secretion of macrophages to promote the proliferation of HCT116 cells via activation of NLRP3 inflammasome and STAT3 pathway in colitis-associated colorectal cancer

Authors: Zhihong Zhang, Mingyue Li, Yi Tai, Yue Xing, Hongxiang Zuo, Xuejun Jin, Juan Ma

Journal: Cell Signal

PubMed ID: 38000525

Doi: 10.1016/j.cellsig.2023.110979

Products & Services: Molecular Biology Reagents

Covalent Peptide LSD1 Inhibitor Specifically Recognizes Cys360 in the Enzyme-Active Region

Authors: Qinhong Luo , Yue Ma , Huiting Liang , Yuan Feng , Na Liu, Chenshan Lian , Lizhi Zhu , Yuxin Ye , Zhihong Liu , Zhanfeng Hou , Sijin Chen , Yaqi Wang , Chuan Dai , Chunli Song , Min Zhang , Zhipeng He , Yun Xing , Wanjin Zhong , Shuiming Li , Jianlong Wu , Fei Lu , Feng Yin , Zigang Li

Journal: J Med Chem .

PubMed ID: 37922441

Doi: 10.1021/acs.jmedchem.3c01549

Products & Services: Gene Synthesis

An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions

Authors: Cailin E Deal, Angelene F Richards, Tracy Yeung, Max J Maron, Ziqiu Wang, Yen-Ting Lai, Brian R Fritz, Sunny Himansu, Elisabeth Narayanan, Ding Liu, Rositsa Koleva, Stuart Licht, Chiaowen J Hsiao, Ivana L Rajlic, Hillary Koch, Michael Kleyman, Mark E Pulse, William J Weiss, Jennifer E Doering, Samantha K Lindberg, Nicholas J Mantis, Andrea Carfi, Obadiah J Plante

Journal: Cell Rep Med

PubMed ID: 37918405

Doi: 10.1016/j.xcrm.2023.101253

Products & Services: Proteins, Expression, Isolation and Analysis

Low-sugar universal mRNA vaccine against coronavirus variants with deletion of glycosites in the S2 or stem of SARS-CoV-2 spike messenger RNA (mRNA)

Authors: Cheng-Wei Cheng, Chung-Yi Wu, Szu-Wen Wang, Jia-Yan Chen, Chih-Chuan Kung, Kuo-Shiang Liao, Chi-Huey Wong

Journal: Proc Natl Acad Sci U S A

PubMed ID: 38011546

Doi: 10.1073/pnas.2314392120

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a sandwich ELISA to detect circulating, soluble IRAP as a potential disease biomarker

Authors: Anika Vear, Claudia Thalmann, Kristina Youngs, Natalie Hannan, Tracey Gaspari, Siew Yeen Chai

Journal: Sci Rep

PubMed ID: 38001104

Doi: 10.1038/s41598-023-44038-1

Products & Services: Proteins, Expression, Isolation and Analysis

Effect of Neutralizing Monoclonal Antibody Treatment on Early Trajectories of Virologic and Immunologic Biomarkers in Patients Hospitalized With COVID-19

Authors: Tomas O Jensen, Greg A Grandits, Mamta K Jain, Thomas A Murray, Birgit Grund, Kathryn Shaw-Saliba, Michael A Matthay, Mahsa Abassi, Magdalena Ardelt, Jason V Baker, Peter Chen, Robin L Dewar, Anna L Goodman, Timothy J Hatlen, Helene C Highbarger, Mark Holodniy, Perrine Lallemand, Sylvain Laverdure, Bradley G Leshnower, David Looney, Charalampos D Moschopoulos, Henry Mugerwa, Daniel D Murray, Eleftherios Mylonakis, Stephanie Nagy-Agren, M Tauseef Rehman, Adam Rupert, Randy A Stevens, Stuart Turville, Amy Weintrob, Katherine Wick, Jens Lundgren, Emily R Ko

Journal: J Infect Dis

PubMed ID: 37948759

Doi: 10.1093/infdis/jiad446

Products & Services: Proteins, Expression, Isolation and Analysis

Self-Entrapment of Antimicrobial Peptides in Silica Particles for Stable and Effective Antimicrobial Peptide Delivery System

Authors: Mi-Ran Ki, Sung Ho Kim, Tae In Park, Seung Pil Pack

Journal: Int J Mol Sci

PubMed ID: 38003614

Doi: 10.3390/ijms242216423

Products & Services: Peptide Synthesis

Engineering U1-Based Tetracycline-Inducible Riboswitches to Control Gene Expression in Mammals

Authors: Eric Rovira, Beatriz Moreno, Nerea Razquin, Lorea Blázquez, Ruben Hernández-Alcoceba, Puri Fortes, Fernando Pastor