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Local Charge Distributions, Electric Dipole Moments, and Local Electric Fields Influence Reactivity Patterns and Guide Regioselectivities in α-Ketoglutarate-Dependent Non-heme Iron Dioxygenases
Authors: Sam P de Visser, Gourab Mukherjee, Hafiz Saqib Ali, Chivukula V Sastri
Journal: Acc Chem Res
PubMed ID: 34915695
Doi: 10.1021/acs.accounts.1c00538
Products & Services: Custom Vector Construction   
SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection
Authors: Sandile Cele, Laurelle Jackson, David S Khoury, Khadija Khan, Thandeka Moyo-Gwete, Houriiyah Tegally, James Emmanuel San, Deborah Cromer, Cathrine Scheepers, Daniel Amoako, Farina Karim, Mallory Bernstein, Gila Lustig, Derseree Archary, Muneerah Smith, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Shi-Hsia Hwa, Jennifer Giandhari, Jonathan M Blackburn, Bernadett I Gosnell, Salim S Abdool Karim, Willem Hanekom, Anne von Gottberg, Jinal Bhiman, Richard J Lessells, Mahomed-Yunus S Moosa, Miles P Davenport, Tulio de Oliveira, Penny L Moore, Alex Sigal
Journal: medrxiv
PubMed ID: 34909788
Doi: 10.1101/2021.12.08.21267417
Products & Services: Monoclonal Antibody Services   
Chlorogenic Acid-Induced Gut Microbiota Improves Metabolic Endotoxemia
Authors: Xiaolin Ye, Yang Liu, Jiajin Hu, Yanyan Gao, Yanan Ma, Deliang Wen
Journal: Front Endocrinol (Lausanne)
PubMed ID: 34975748
Doi: 10.3389/fendo.2021.762691
Products & Services: Endotoxin Detection & Removal System   
Constructing DNA logic circuits based on the toehold preemption mechanism
Authors: Cuicui Xing, Xuedong Zheng, Qiang Zhang
Journal: RSC Adv
PubMed ID: 35424506
Doi: 10.1039/d1ra08687a
Products & Services: Gene Synthesis   
Heterologous prime-boost immunizations with chimpanzee adenoviral vectors elicit potent and protective immunity against SARS-CoV-2 infection
Authors: Jiaojiao Liu, Kun Xu, Man Xing, Yue Zhuo, Jingao Guo, Meng Du, Qi Wang, Yaling An, Jinhe Li, Ping Gao, Yihan Wang, Furong He, Yingying Guo, Mingxi Li, Yuchao Zhang, Linqi Zhang, George F Gao, Lianpan Dai, Dongming Zhou
Journal: Cell Discov
PubMed ID: 34923570
Doi: 10.1038/s41421-021-00360-4
Products & Services: Catalog Peptides   
Platelet Endothelial Cell Adhesion Molecule 1 (CD31) Is Essential for Beta-Toxin Mediated Cytotoxicity in Human Endothelial and Monocytic Cells
Authors: Basma Tarek, Julia Bruggisser, Filippo Cattalani, Horst Posthaus
Journal: Toxins (Basel)
PubMed ID: 34941730
Doi: 10.3390/toxins13120893
Products & Services: Recombinant Antibody Expression   
Small molecule splicing modifiers with systemic HTT-lowering activity
Authors: Anuradha Bhattacharyya, Christopher R Trotta, Jana Narasimhan, Kari J Wiedinger, Wencheng Li, Kerstin A Effenberger, Matthew G Woll, Minakshi B Jani, Nicole Risher, Shirley Yeh, Yaofeng Cheng, Nadiya Sydorenko, Young-Choon Moon, Gary M Karp, Marla Weetall, Amal Dakka, Vijayalakshmi Gabbeta, Nikolai A Naryshkin, Jason D Graci, Thomas Tripodi, Amber Southwell, Michael Hayden, Joseph M Colacino, Stuart W Peltz
Journal: Nat Commun
PubMed ID: 34911927
Doi: 10.1038/s41467-021-27157-z
Products & Services: Gene Synthesis   
Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2
Authors: Kristen A Rodrigues, Sergio A Rodriguez-Aponte, Neil C Dalvie, Jeong Hyun Lee, Wuhbet Abraham, Diane G Carnathan, Luis E Jimenez, Julia T Ngo, Jason Y H Chang, Zeli Zhang, Jingyou Yu, Aiquan Chang, Catherine Nakao, Benjamin Goodwin, Christopher A Naranjo, Libin Zhang, Murillo Silva, Dan H Barouch, Guido Silvestri, Shane Crotty, J Christopher Love, Darrell J Irvine
Journal: Sci Adv
PubMed ID: 34878851
Doi: 10.1126/sciadv.abj6538
Products & Services: Catalog Antibody   
Creation of a recombinant Komagataella phaffii strain, a producer of proteinase K from Tritirachium album
Authors: A B Beklemishev, M B Pykhtina, Ya M Kulikov, T N Goryachkovskaya, D V Bochkov, S V Sergeeva, A R Vasileva, V P Romanov, D S Novikova, S E Peltek
Journal: Vavilovskii Zhurnal Genet Selektsii
PubMed ID: 35083407
Doi: 10.18699/VJ21.102
Products & Services: Bacterial Expression   
An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade
Authors: Shuguang Zuo, Min Wei, Tiancheng Xu, Lingkai Kong, Bohao He, Shiqun Wang, Shibing Wang, Junhua Wu, Jie Dong, Jiwu Wei
Journal: J Immunother Cancer
PubMed ID: 34949694
Doi: 10.1136/jitc-2021-002843
Products & Services: GenParts™ DNA Fragments   

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