目录产品 » HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Monomer[Biotin], His & Avi, Human
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HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Monomer[Biotin], His & Avi, Human

Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
￥4900
Z06818-100

产品简介
Species Human
Protein Construction
HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Monomer[Biotin][ Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and LTLGEFLKL peptide]
Accession # A0A140T913(HLA-A*02:01)&P61769(B2M)& LTLGEFLKL		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 50.44 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Concentration Verified by one or more methods from A280/Bioactivity/BCA/Bradford.
Storage & Stability Upon receiving, the product remains stable for 6 months at -80 °C or below. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
Synonyms Survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.