目录产品 » HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control, His & Avi, Human
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HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control, His & Avi, Human

HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules performed by cytotoxic lymphocytes.
￥3000
Z06644-100

产品简介
Species Human
Protein Construction
HLA-E*01:03&B2M&Peptide (VMAPKTLVL) Monomer Negative Control[Gly22-Thr302(HLA-E*01:03), Ile21-Met119(B2M) and VMAPKTLVL peptide]
Accession # P13747(HLA-E*01:03)&P61769(B2M)&VMAPKTLVL		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 50.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 52-62 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background HLA-E is a nonclassical member of the major histocompatibility complex class I gene locus. HLA-E protein shares a high level of homology with MHC Ia classical proteins: it has similar tertiary structure, associates with β2-microglobulin, and is able to present peptides to cytotoxic lymphocytes. The main function of HLA-E under normal conditions is to present peptides derived from the leader sequences of classical HLA class I proteins, thus serving for monitoring of expression of these molecules performed by cytotoxic lymphocytes.
Synonyms HLAE; sHLA-E; HLAE; MHC class I antigen E; MHC; QA1
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.