目录产品 » HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human
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HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human

Melanoma-associated antigen 4 is a protein that in humans is encoded by the MAGEA4 gene.The MAGE- A4 antigen is among the most commonly expressed cancer testis antigens. The Human HLA-A*0201 MAGE-A4 (GVYDGREHTV) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and GVYDGREHTV peptide of the MAGE-A4.
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产品简介
Species Human
Protein Construction
HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer [Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GVYDGREHTV peptide]
Accession # A0A140T913(HLA-A*02:01)&P61769(B2M)&GVYDGREHTV		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 258 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human

Immobilized HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Antibody, hFc Tag with the EC50 of 3.9 ng/ml determined by ELISA. »

HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human

The purity of HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human is greater than 95% as determined by SEC-HPLC. »

HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human

HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%. »

HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human

Anti-HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Antibody, hFc Tag captured on CM5 Chip via Protein A can bind HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer, His & Avi, Human, His Tag with an affinity constant of 8.49pM as determined in SPR assay (Biacore T200). »

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技术背景
Target Background Melanoma-associated antigen 4 is a protein that in humans is encoded by the MAGEA4 gene.The MAGE- A4 antigen is among the most commonly expressed cancer testis antigens. The Human HLA-A*0201 MAGE-A4 (GVYDGREHTV) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and GVYDGREHTV peptide of the MAGE-A4.
Synonyms HLA0201; MHC I; MAGE-A4; CT1.4; MAGE4A; MAGE4B; MAGE-X2; member 4
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.